A flawed study should not define a new standard of care.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. DEGRO practical guideline for partial-breast irradiation.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
   Guideline
2. Accelerated partial breast irradiation with external beam radiotherapy : First results of the German phase 2 trial.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2017
   Trial
3. Intraoperative Radiation Therapy (IORT) for Breast Cancer: The Final Analysis of a Prospective Cohort of 1828 Cases.Annals of surgical oncology · 2025
   Article
4. Case Report: Intraoperative radiotherapy as the new standard of care for breast cancer patients with disabling health conditions or impairments.Frontiers in oncology · 2023
   Article
5. Evolution of radiotherapy techniques in breast conservation treatment.Gland surgery · 2018
   Review
6. In vivo dosimetry and acute toxicity in breast cancer patients undergoing intraoperative radiotherapy as boost.Radiation oncology journal · 2017
   Article
7. Intraoperative radiation therapy for breast cancer patients: current perspectives.Breast cancer (Dove Medical Press) · 2017
   Review
8. Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.International journal of radiation oncology, biology, physics · 2015
   Article

Corrections and comments

• Commented on by
  Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.2015
• Commented on by
  In Regard to Hepel and Wazer.2015
• Commented on by
  In Regard to Hepel and Wazer.2015
• Commented on by
  In Regard to Hepel and Wazer.2015
• Commented on by
  In Regard to Hepel and Wazer.2015
• Comment on
  Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.2014

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as