ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2015
Validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) in individuals with Huntington disease (HD).
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Open Label 8-Week Study of Prazosin Use in Adults With Anxiety Disorders
Web-based Follow-up to Former ICU Patients
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Measurement characteristics of WHODAS 2.0 and WHODAS-Child: a systematic review of global psychometric studies in specific populations since 2010.Frontiers in psychiatry · 2026Pooled it
- Health state utility estimates for value assessments of novel treatments in Huntington's disease: a systematic literature review.Health and quality of life outcomes · 2024Pooled it
- Effects of exercise training on bone mineral density and some health-related outcomes in HIV conditions: A randomized controlled trial.Medicine · 2020Trial
- Post-COVID-19 anxiety and its impact on adults' health in Qatar in 2022.Qatar medical journal · 2026Article
- Article
- Validation of the 12-item World Health Organization Disability Assessment Schedule (WHODAS 2.0) in adults with attention-deficit hyperactivity disorder.BJPsych open · 2025Article
- Observational
- Article
- Article
- Multimorbidity and adverse longitudinal outcomes among patients attending chronic outpatient medical care in Bahir Dar, Northwest Ethiopia.Frontiers in medicine · 2023Article
- Measurement and Validation of the Comprehensive Score for Financial Toxicity (COST) in a Population With Diabetes.Diabetes care · 2022Article
- Multimorbidity and health-related quality of life among patients attending chronic outpatient medical care in Bahir Dar, Northwest Ethiopia: The application of partial proportional odds model.PLOS global public health · 2022Article
- Clinical Decision Trees to Guide Physical Therapy Management of Persons with Huntington's Disease.Journal of Huntington's disease · 2022Review
- Assessing Functioning across Common Mental Disorders in Psychiatric Emergency Patients: Results from the WHODAS-2.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Article
- Article
- Adapting World Health Organization Disability Assessment Schedule 2.0 for Nepal.BMC psychology · 2021Article
- Psychometric Properties and Validation of the Polish Version of the 12-Item World Health Organization Disability Assessment Schedule 2.0 in Patients with Huntington's Disease.Journal of clinical medicine · 2021Article
- Understanding speech and swallowing difficulties in individuals with Huntington disease: Validation of the HDQLIFE Speech Difficulties and Swallowing Difficulties Item Banks.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Quality of Life and Functioning of People With Mental Disorders Who Underwent Deinstitutionalization Using Assisted Living Facilities: A Cross-Sectional Study.Frontiers in psychology · 2021Article
- Minimal clinically important difference and minimal detectable change of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) amongst patients with chronic musculoskeletal pain.Clinical rehabilitation · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeThe reliability and construct validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) were examined in individuals with Huntington disease (HD).
methodsWe examined factor structure (confirmatory factor analysis), internal consistency reliability (Cronbach's alpha), floor and ceiling effects, convergent validity (Pearson correlations), and known-groups validity (multivariate analysis).
resultsResults of a confirmatory factor analysis replicated the six-factor latent model that reflects the six separate scales within the WHODAS 2.0 (understanding and communicating; getting around; self-care; getting along with others; life activities; participation). Cronbach's alpha for the scale was 0.94, suggesting good internal consistency reliability. The WHODAS demonstrated a ceiling effect for 19.5 % of participants; there were no floor effects. There was evidence for convergent validity; the WHODAS demonstrated moderate significant correlations with other general measures of health-related quality of life (HRQOL; i.e., RAND-12, EQ5D). Multivariate analyses indicated that late-stage HD participants indicated poorer HRQOL than both early-stage HD and prodromal HD participants for all HRQOL measures.
conclusionsFindings provide support for both the reliability and validity of the WHODAS 2.0 in individuals with HD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.