Evidence map›Paper›PMID 25636442›Full record

SynthesisEndocrine2015

Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy.

Annie-Claude M Lassemillante, Suhail A R Doi, John D Hooper, John B Prins, Olivia R L Wright

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Endocrine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Prevalence of osteoporosis and low bone mass in men with prostate cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Canadian Urological Association best practice report: Bone health in prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Health status of older cancer survivors-results of the PolSenior study.Journal of cancer survivorship : research and practice · 2018
    Article
  16. Review
  17. Review
  18. Article
  19. Prevention and treatment of bone fragility in cancer patient.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
    Review
  20. SIMBOSPROST: Prevalence of metabolic syndrome and osteoporosis in prostate cancer patients treated with radiotherapy and androgen deprivation therapy: A multicentre, cross-sectional study.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Annie-Claude M LassemillanteCentre for Dietetics Research (C-DIET-R), School of Human Movement and Nutrition Science, The University of Queensland, St Lucia, QLD, 4072, Australia. a.lassemillante@uq.edu.au.
Suhail A R DoiClinical Epidemiology Unit, School of Population Health, The University of Queensland, Herston, QLD, 4006, Australia.
John D HooperMater Research Institute, University of Queensland, Kent Street, Woolloongabba, QLD, 4102, Australia.
John B PrinsMater Research Institute, University of Queensland, Kent Street, Woolloongabba, QLD, 4102, Australia.
Olivia R L WrightCentre for Dietetics Research (C-DIET-R), School of Human Movement and Nutrition Science, The University of Queensland, St Lucia, QLD, 4072, Australia.
University of Queensland · AUMater Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of osteoporosis in men with prostate cancer (PCa) on androgen deprivation therapy (ADT) is well documented, with up to 53% affected by this bone condition. However, there has been less emphasis on the burden of severe bone loss in men with PCa but not undergoing ADT. Therefore, the purpose of this meta-analysis is to compile evidence from the literature on the bone health of hormone-naïve PCa patients and to compare it to the bone health of men with PCa on ADT. Three databases were searched for the relevant literature published from 1990 until January 2014. The pooled prevalence of osteoporosis, low bone mass, and normal bone mass were estimated for this patient group and compared with similar subgroups from a previously published meta-analysis. The prevalence of osteoporosis varies from 4 to 38% in hormone-naïve PCa patients, and men with more advanced disease have a higher prevalence of osteoporosis. Men with PCa on ADT have poorer bone health than their hormone-naïve counterparts, but the trend toward poorer bone health with metastatic disease remains. In conclusion, it was found that men with PCa experience poor bone health prior to treatment with ADT. These results suggest that all men with PCa should have regular bone health monitoring, whether they commence ADT or not, in order to prevent or indeed minimize the morbidity that accompanies osteoporosis.

Indexed as

AgedAged, 80 and overAndrogen AntagonistsHumansMaleMiddle AgedOsteoporosisProstatic NeoplasmsAndrogen AntagonistsAndrogen deprivation therapyBone healthMeta-analysisOsteopeniaOsteoporosisProstate cancer

Identifiers

PMID25636442
OpenAlexW2042356460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.