Evidence map›Paper›PMID 25636441›Full record

Trial reportEndocrine2015

Effects of the anti-inflammatory drug salsalate on bone turnover in type 2 diabetes mellitus.

Mishaela R Rubin, Allison B Goldfine, Donald J McMahon, Daniel S Donovan, Serge Cremers, Elzbieta Dworakowski, Ernst J Schaefer, Steven E Shoelson, Shonni J Silverberg

Abstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Endocrine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mishaela R RubinMetabolic Bone Diseases Unit, Department of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA. mrr6@columbia.edu.
Allison B GoldfineJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Donald J McMahonMetabolic Bone Diseases Unit, Department of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA.
Daniel S DonovanDepartment of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA.
Serge CremersMetabolic Bone Diseases Unit, Department of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA.
Elzbieta DworakowskiMetabolic Bone Diseases Unit, Department of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA.
Ernst J SchaeferLipid Metabolism Laboratory, Tufts University, Boston, MA, USA.
Steven E ShoelsonJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Shonni J SilverbergMetabolic Bone Diseases Unit, Department of Medicine, College of Physicians & Surgeons, Columbia University, 630 W. 168th St, New York, NY, 10032, USA.
Columbia University · USJoslin Diabetes Center · USTufts University · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$50.5M
Weight Loss, Inflammation, and Vascular RemodelingP50HL083813 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WELTY, FRANCINE K · 2006 to 2015
$13.0M
Targeting Inflammation in Type 2 Diabetes: Clinical Trial Using SalsalateU01DK074556 · NIDDK · JOSLIN DIABETES CENTER · PI SHOELSON, STEVEN E · 2006 to 2010
$7.8M
Non-Classical Manifestations of Primary HyperparathyroidismK24DK074457 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVERBERG, SHONNI J · 2006 to 2016
$1.7M
The Skeletal Effects of Reducing Inflammation in Type 2 Diabetes MellitusRC4DK090776 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RUBIN, MISHAELA R · 2010 to 2010
$400k
NHLBI NIH HHS P50 HL083813NIDDK NIH HHS K24 DK074457NIDDK NIH HHS P01 DK036836NIDDK NIH HHS P30 DK036836NIDDK NIH HHS RC4 DK090776NIDDK NIH HHS U01 DK074556NIDDK NIH HHS U01 DK74556
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalBiomarkersBone RemodelingDiabetes Mellitus, Type 2HumansInflammationOsteocalcinSalicylatesTreatment OutcomeAnti-Inflammatory Agents, Non-SteroidalBiomarkersOsteocalcinSalicylatessalicylsalicylic acid

Identifiers

PMID25636441
PMCPMC4522229
OpenAlexW1971376455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.