Trial reportEuropean radiology2015
Radiation dose and image quality of 70 kVp cerebral CT angiography with optimized sinogram-affirmed iterative reconstruction: comparison with 120 kVp cerebral CT angiography.
Trial report in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02971176 (Low-dose Protocol for Computed Tomography-guided Lung Biopsy), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Low-dose Protocol for Computed Tomography-guided Lung Biopsy
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Computed Tomography of the Head : A Systematic Review on Acquisition and Reconstruction Techniques to Reduce Radiation Dose.Clinical neuroradiology · 2023Pooled it
- Deep Learning-Based Augmented Contrast-Enhancement and Denoising for Reduced-Iodine and Low-Radiation 70-kVp Cerebral CT Angiography: A Prospective Study.Korean journal of radiology · 2026Trial
- Exploration of thoracoabdominal aortic mixed reality optimisation and its clinical application value in type A aortic dissection.European radiology · 2023Trial
- Carotid CTA at the Lowest Tube Voltage (70 kV) in Comparison with Automated Tube Voltage Adaption.AJNR. American journal of neuroradiology · 2019Trial
- Head and neck angiography at 70 kVp with a third-generation dual-source CT system in patients: comparison with 100 kVp.Neuroradiology · 2017Trial
- Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study.European radiology · 2016Trial
- Exploring double low-dose CT technology for achieving coronary mixed reality radiation dose reduction: a preliminary study in coronary artery disease patients.Quantitative imaging in medicine and surgery · 2026Article
- Balancing Radiation Dose and Image Quality: Protocol Optimization for Mobile Head CT in Neurointensive Care Unit Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Application of bolus tracking: The effect of ROI positions on the images quality of cervicocerebral CT angiography.Heliyon · 2024Article
- A comparative study of low voltage, low contrast cerebral computed tomography angiography with iterative reconstruction and conventional cerebral computed tomography angiography.The neuroradiology journal · 2024Article
- Feasibility of using 8 mL of iodinated contrast media in cerebral computed tomographic angiography with a dual-layer spectral detector.Quantitative imaging in medicine and surgery · 2024Article
- Effects of the Sn100 kVp Tube Voltage Mode on the Radiation Dose and Image Quality of Dual-Source Computed Tomography Pulmonary Angiography.International journal of general medicine · 2021Article
- A clinically applicable deep-learning model for detecting intracranial aneurysm in computed tomography angiography images.Nature communications · 2020Article
- Computed tomography-guided lung biopsy: a randomized controlled trial of low-dose versus standard-dose protocol.European radiology · 2020Article
- Sinogram-Affirmed Iterative Reconstruction Negatively Impacts the Risk Category Based on Agatston Score: A Study Combining Coronary Calcium Score Measurement and Coronary CT Angiography.BioMed research international · 2020Article
- Dual-energy CT angiography-derived virtual non-contrast images for follow-up of patients with surgically clipped aneurysms: a retrospective study.Neuroradiology · 2019Article
- Radiation dose and image quality in intraoperative CT (iCT) angiography of the brain with stereotactic head frames.European radiology · 2019Article
- Digital subtraction CT angiography for the detection of posterior inferior cerebellar artery aneurysms: comparison with digital subtraction angiography.European radiology · 2017Article
- Feasibility of dual-low scheme combined with iterative reconstruction technique in acute cerebral infarction volume CT whole brain perfusion imaging.Experimental and therapeutic medicine · 2017Article
- Cerebral bone subtraction CT angiography using 80 kVp and sinogram-affirmed iterative reconstruction: contrast medium and radiation dose reduction with improvement of image quality.Neuroradiology · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate radiation dose, image quality, and optimal level of sinogram-affirmed iterative reconstruction (SAFIRE) of cerebral CT angiography (CTA) at 70 kVp.
methodsOne hundred patients were prospectively classified into two groups: Group A (n = 50), 70 kVp cerebral CTA with 5 levels of SAFIRE reconstruction (S1-S5); and Group B (n = 50), 120 kVp with filtered back projection (FBP) reconstruction. CT attenuation values, noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the internal carotid artery (ICA) and middle cerebral artery (MCA) were measured. Subjective image quality was evaluated. Effective dose (ED) was estimated.
resultsCT attenuation and noise of the ICA and MCA in Group A were higher than those of Group B (all P < 0.001) while the SNRICA, SNRMCA, CNRICA, and CNRMCA of Group A at S4-5 were comparable to (P > 0.05) or higher than in Group B (P < 0.05). There was no difference in overall image quality between Group A S3-5 and Group B (P > 0.05). ED was 0.2 ± 0.0 mSv for Group A with 85 % ED reduction in comparison to Group B (1.3 ± 0.2 mSv).
conclusionCerebral CTA at 70 kVp is feasible, allowing for substantial radiation dose reduction. SAFIRE S4 level is recommended for obtaining optimal image quality. KEY POINTS: • 70 kVp cerebral CTA is feasible and provides diagnostic image quality. • 70 kVp cerebral CTA resulted in 85% effective dose reduction. • S4 level of SAFIRE is recommended for 70 kVp cerebral CTA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.