ArticlePlant molecular biology2015
RNA-Seq analysis of rye-grass transcriptomic response to an herbicide inhibiting acetolactate-synthase identifies transcripts linked to non-target-site-based resistance.
Article in Plant molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 150 citations in OpenAlex.
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- Metabolism-Based Herbicide Resistance to Mesosulfuron-methyl and Identification of Candidate Genes inPlants (Basel, Switzerland) · 2024Article
- Weed biology and management in the multi-omics era: Progress and perspectives.Plant communications · 2024Review
- Genomic characterisation and dissection of the onset of resistance to acetyl CoA carboxylase-inhibiting herbicides in a large collection ofFrontiers in genetics · 2024Article
- Assessment of ACC and P450 Genes Expression in Wild Oat (Avena ludoviciana) in Different Tissues Under Herbicide Application.Biochemical genetics · 2023Article
- Plant Metabolomics: An Overview of the Role of Primary and Secondary Metabolites against Different Environmental Stress Factors.Life (Basel, Switzerland) · 2023Review
- Distinctive physiological and molecular responses of foxtail millet and maize to nicosulfuron.Frontiers in plant science · 2023Article
- First Report of the Molecular Mechanism of Resistance to Tribenuron-Methyl inPlants (Basel, Switzerland) · 2022Article
- Diversity of Herbicide-Resistance Mechanisms ofPlants (Basel, Switzerland) · 2022Article
- Cytochrome P450 CYP709C56 metabolizing mesosulfuron-methyl confers herbicide resistance in Alopecurus aequalis.Cellular and molecular life sciences : CMLS · 2022Article
- Expression stability of internal reference gene in response to Trichoderma polysporum infection in Avena fatua L.Current genetics · 2021Article
- Differential expression of genes associated with non-target site resistance in Poa annua with target site resistance to acetolactate synthase inhibitors.Pest management science · 2021Article
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- Understanding Resistance Mechanisms to Trifluralin in an Arkansas Palmer Amaranth Population.Genes · 2021Article
- Adaptive and maladaptive expression plasticity underlying herbicide resistance in an agricultural weed.Evolution letters · 2021Article
- Whole transcriptome analysis resulted in the identification of Chinese sprangletop (Leptochloa chinensis) genes involved in cyhalofop-butyl tolerance.BMC genomics · 2021Article
- Transcriptome analysis reveals gene responses to herbicide, tribenuron methyl, in Brassica napus L. during seed germination.BMC genomics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-target-site resistance (NTSR) to herbicides that disrupts agricultural weed control is a worldwide concern for food security. NTSR is considered a polygenic adaptive trait driven by differential gene regulation in resistant plants. Little is known about its genetic determinism, which precludes NTSR diagnosis and evolutionary studies. We used Illumina RNA-sequencing to investigate transcriptomic differences between plants from the global major weed rye-grass sensitive or resistant to the acetolactate-synthase (ALS) inhibiting herbicide pyroxsulam. Plants were collected before and along a time-course after herbicide application. De novo transcriptome assembly yielded a resource (LOLbase) including 92,381 contigs representing potentially active transcripts that were assigned putative annotations. Early effects of ALS inhibition consistent with the literature were observed in resistant and sensitive plants, proving LOLbase data were relevant to study herbicide response. Comparison of resistant and sensitive plants identified 30 candidate NTSR contigs. Further validation using 212 plants resistant or sensitive to pyroxsulam and/or to the ALS inhibitors iodosulfuron + mesosulfuron confirmed four contigs (two cytochromes P450, one glycosyl-transferase and one glutathione-S-transferase) were NTSR markers which combined expression levels could reliably identify resistant plants. This work confirmed that NTSR is driven by differential gene expression and involves different mechanisms. It provided tools and foundation for subsequent NTSR investigations.
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