Evidence map›Paper›PMID 25636187›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

HAM/TSP and major depression: the role of age.

Ney Boa-Sorte, Ana Verena Galvão-Castro, Danilo Borba, Renan Barbalho Nunes de Castro Lima, Bernardo Galvão-Castro

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Epidemiology and Clinical Outcomes of HTLV-1: A Comprehensive Narrative Review of Endemic and Nonendemic Regions.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Quality of life, risk behaviors and depression among carriers of hepatitis C virus and human T-cell lymphotropic virus type 1: a comparative study.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ney Boa-SorteReference Center for HTLV, Bahiana School of Medicine and Public Health Salvador, Salvador, BA, Brazil. Electronic address: neyboasorte@bahiana.edu.br.
Ana Verena Galvão-CastroReference Center for HTLV, Bahiana School of Medicine and Public Health Salvador, Salvador, BA, Brazil.
Danilo BorbaFoundation for Science Development, Salvador, BA, Brazil.
Renan Barbalho Nunes de Castro LimaReference Center for HTLV, Bahiana School of Medicine and Public Health Salvador, Salvador, BA, Brazil.
Bernardo Galvão-CastroReference Center for HTLV, Bahiana School of Medicine and Public Health Salvador, Salvador, BA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of demographic variables in the relationship between the presence of HAM/TSP and current major depression.

methodsIt is a cross-sectional study of 108 HTLV-1 infected patients (47 with TSP/HAM) resident of Salvador, Brazil. The Mini International Neuropsychiatric Interview, Brazilian Version 5 was used to evaluate the presence of depression. Prevalence ratios were used to describe relationship between HAM/TSP and depression. The HAM/TSP classification was carried out according to the criteria proposed by Castro-Costa et al.

resultsPrevalence of depression was 37.96%. No association was observed between presence of HAM/TSP and diagnosis of current major depression in the global analysis of patients (PR: 0.94; CI 95%: 0.57-1.55). In the stratified analysis, however, greater prevalence of depression was observed amongst individuals with HAM/TSP in the 18-39 age group (PR: 2.59; CI 95%: 1.36-4.95).

conclusionOur findings suggest that age is an effect modifier in the relationship between HAM/TSP and depression, and this aspect should be considered in future studies on the topic.

Indexed as

Human T-lymphotropic virus 1AdolescentAdultBrazilCross-Sectional StudiesFemaleHumansMajor Depressive DisorderMaleMiddle AgedParaparesis, Tropical SpasticPrevalenceSocioeconomic FactorsViral LoadYoung AdultAge factorsDepressionHTLV-1 associated myelopathiesHuman T-lymphotropic virus 1

Identifiers

PMID25636187
PMCPMC9425409

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.