Evidence map›Paper›PMID 25636183›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae causing noninvasive diseases in a Children's Hospital, Shanghai.

Fen Pan, Lizhong Han, Jing Kong, Chun Wang, Huihong Qin, Shuzhen Xiao, Junying Zhu, Hong Zhang

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Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence ofHuman vaccines & immunotherapeutics · 2024
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Serotype distribution and antimicrobial resistance ofIranian journal of microbiology · 2022
    Article
  8. Epidemiology Characteristics ofFrontiers in cellular and infection microbiology · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fen PanDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China.
Lizhong HanDepartment of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Jing KongDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China.
Chun WangDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China.
Huihong QinDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China.
Shuzhen XiaoDepartment of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Junying ZhuDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China.
Hong ZhangDepartment of Clinical Laboratory, Children's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, China. Electronic address: Zhanghong3010@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptococcus pneumoniae, which cause noninvasive pneumococcal diseases, severely impair children's health. This study analyzed serotype distribution and antimicrobial resistance of S. pneumoniae from January 2012 to December 2012 in a Children's Hospital, Shanghai.

methodsA total of 328 pneumococcal isolates were serotyped by multiplex sequential PCR and/or capsule-quellung reaction. The minimum inhibitory concentrations for 11 antimicrobial agents were determined by broth microdilution method.

resultsAmong 328 strains, 19F (36.3%), 19A (13.4%), 6A (11.9%), 23F (11.0%), 14 (5.8%), 6B (5.2%), and 15B/C (4.3%) were the most common serotypes. The coverage rates of 7-, 10-, and 13-valent conjugate vaccines (PCV7, PCV10, and PCV13) were 58.2%, 58.2%, and 84.1%, respectively. Out of the isolates, 26 (7.9%) strains were penicillin resistant. Most of the strains displayed high resistance rate to macrolides (98.5% to erythromycin, 97.9% to azithromycin, and 97.0% to clindamycin).

conclusionsThe potential coverage of PCV13 is higher than PCV7 and PCV10 because of the emergence of 19A and there should be long-term and systematic surveillance for non-vaccine serotypes.

Indexed as

AdolescentAnti-Bacterial AgentsChildChild, PreschoolChinaFemaleHumansInfantInfant, NewbornMaleMicrobial Sensitivity TestsMultiplex Polymerase Chain ReactionPneumococcal InfectionsPopulation SurveillanceSerotypingStreptococcus pneumoniaeAnti-Bacterial AgentsAntimicrobial resistanceSerotypeStreptococcus pneumoniae

Identifiers

PMID25636183
PMCPMC9425176

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.