ReviewCurrent opinion in pediatrics2015
Impact of hospital-based environmental exposures on neurodevelopmental outcomes of preterm infants.
Review in Current opinion in pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Sleeping Environment on Sleep-Wake Organization in Preterm Infants
Effects of Neonatal Therapeutic Touch and Massage in Very Preterm and Extremely Preterm Neonates: A Randomized Controlled Trial
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Opportunities and Challenges of Using Artificial Intelligence in Predicting Clinical Outcomes and Length of Stay in Neonatal Intensive Care Units: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Effectiveness of interventions on early neurodevelopment of preterm infants: a systematic review and meta-analysis.BMC pediatrics · 2021Pooled it
- The effect of donor human milk on the length of hospital stay in very low birthweight infants: a systematic review and meta-analysis.International breastfeeding journal · 2020Pooled it
- Defining the developmental exposome of the neonatal intensive care unit in preterm infants.Journal of exposure science & environmental epidemiology · 2026Article
- Fathers, not mothers: the male singing voice and the preterm brain's response to song in the NICU.Pediatric research · 2026Article
- Exploring the Hidden Talents of Preterm Infants: Moving Beyond a Risk-Focused Perspective.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Assessing preterm infant metal exposures in shed teeth: findings from the Developmental Impact of NICU Exposures (DINE) study.Journal of exposure science & environmental epidemiology · 2026Article
- The association between bronchopulmonary dysplasia severity and neurodevelopmental disorders.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Newborn and family-centered care: a scoping review on related newborn rights and principles.Journal of global health · 2026Article
- Machine learning risk stratification for high-risk infant follow-up of term and late preterm infants.Pediatric research · 2026Article
- Design and experimental validation of a soft pneumatic robotic device for preterm infant skin-to-skin tactile therapy.Frontiers in robotics and AI · 2026Article
- Article
- The role of light exposure in infant circadian rhythm establishment: A scoping review perspective.European journal of pediatrics · 2024Article
- Families as partners in neonatal neuro-critical care programs.Pediatric research · 2024Review
- The development of neonatal neurointensive care.Pediatric research · 2024Review
- Evaluation of noise levels and noise sources in an Irish neonatal intensive care unit.Annals of work exposures and health · 2024Article
- Article
- Associations between sociodemographic characteristics and neonatal length of the stay.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- The Effect of Incubator Cover on Newborn Vital Signs: The Design of Repeated Measurements in Two Separate Groups with No Control Group.Children (Basel, Switzerland) · 2023Article
- Exposure of preterm neonates receiving total parenteral nutrition to phthalates and its impact on neurodevelopment at the age of 2 months.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewOver 300,000 infants are hospitalized in a neonatal intensive care unit (NICU) in the United States annually during a developmental period critical to later neurobehavioral function. Environmental exposures during the fetal period and infancy have been shown to impact long-term neurobehavioral outcomes. This review summarizes evidence linking NICU-based environmental exposures to neurodevelopmental outcomes of children born preterm. RECENT
findingsPreterm infants experience multiple exposures important to neurodevelopment during the NICU hospitalization. The physical layout of the NICU, management of light and sound, social interactions with parents and NICU staff, and chemical exposures via medical equipment are important to long-term neurobehavioral outcomes in this highly vulnerable population. SUMMARY: Existing research documents NICU-based exposure to neurotoxic chemicals, aberrant light, excess sound, and restricted social interaction. In total, this creates an environment of co-existing excesses (chemicals, light, sound) and deprivation (touch, speech). The full impact of these co-exposures on the long-term neurodevelopment of preterm infants has not been adequately elucidated. Research into the importance of the NICU from an environmental health perspective is in its infancy, but could provide understanding about critical modifiable factors impacting the neurobehavioral health of hundreds of thousands of children each year.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.