Evidence map›Paper›PMID 25635494›Full record

ArticleAmerican journal of respiratory and critical care medicine2015

Tuberous sclerosis complex 2 loss of heterozygosity in patients with lung disease and cancer.

Li Zhang, Gustavo Pacheco-Rodriguez, Wendy K Steagall, Jiro Kato, Mary Haughey, Joseph R Fontana, Vincent C Manganiello, Joel Moss

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models.American journal of respiratory cell and molecular biology · 2018
    Review
  2. New insights in lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li Zhang1 National Heart, Lung, and Blood Institute Bethesda, Maryland.
Gustavo Pacheco-Rodriguez
Wendy K Steagall
Jiro Kato
Mary Haughey
Joseph R Fontana
Vincent C Manganiello
Joel Moss

Funding

Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)ZIAHL002541 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MOSS, JOEL · 2009 to 2025
$47.7M
Expression, Structure/function, Regulation, and Roles of PDE3 IsoformsZIAHL002540 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MANGANIELLO, VINCENT · 2009 to 2016
$17.0M
Translational Studies in SarcoidosisZIAHL002545 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MANGANIELLO, VINCENT · 2010 to 2014
$206k
Intramural NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Loss of HeterozygosityBiomarkersEvidence-Based MedicineGenotypeHumansLung DiseasesMutationNeoplasmsPhenotypeTuberous SclerosisTuberous Sclerosis Complex 2 ProteinTumor Suppressor ProteinsBiomarkersTuberous Sclerosis Complex 2 ProteinTumor Suppressor Proteins

Identifiers

PMID25635494
PMCPMC4351575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.