ArticleAJNR. American journal of neuroradiology2015
The Curved MCA: Influence of Vessel Anatomy on Recanalization Results of Mechanical Thrombectomy after Acute Ischemic Stroke.
Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mechanical Thrombectomy in the Management of Acute Ischemic Stroke Secondary to Calcified Cerebral Emboli: a Systematic Review.Clinical neuroradiology · 2026Pooled it
- Diving MCA and First-Pass Effect: A Subgroup Analysis From the ARISE II Study.Stroke (Hoboken, N.J.) · 2026Article
- Endovascular thrombectomy for stroke due to medium vessel occlusion: a meta-analysis of randomized controlled trials.Annals of medicine and surgery (2012) · 2026Article
- Impact of Middle Cerebral Artery Branching Patterns on Mechanical Thrombectomy Outcomes for M1 Occlusion.Neurologia medico-chirurgica · 2026Article
- Progress on using CTA-based vessel distance index to predict futile recanalization: a retrospective observational study.BMC neurology · 2026Observational
- Impact of Intracranial Arterial Calcification on Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Journal of neuroendovascular therapy · 2026Article
- Single-Phase CTA Guided by the Time-Enhancement Curve Derived from CT Perfusion for Mechanical Thrombectomy.Journal of neuroendovascular therapy · 2026Article
- Thrombectomy for medium-sized cerebral vessel occlusion: Size does matter.European stroke journal · 2026Observational
- Prognostic value of intracranial vascular tortuosity in thrombectomy for distal vessel occlusion.European stroke journal · 2026Article
- Does initiating aspiration with microcatheter navigation improve the efficacy of thrombectomy in acute ischemic stroke patients with vascular angulation at the level of occlusion?Neuroradiology · 2025Article
- Push and Fluff technique for optimization of clot integration with stent-retriever: An in vitro model.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Thrombectomy for medium-sized cerebral vessel occlusion: Size does matter.European stroke journal · 2025Article
- Investigation of thrombectomy technique for M2 occlusion based on the M1-M2 bifurcation angle.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Prognostic value of intracranial vascular tortuosity in thrombectomy for distal vessel occlusion.European stroke journal · 2025Article
- Development of an in-vitro model based on patient vessel geometry for simulated use testing in neurointerventional surgery.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Combined technique versus stent-retriever alone: Interaction analysis of angioarchitectural and technical features.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Analysis of gradual diameter thrombectomy stentTranslational neuroscience · 2025Article
- Variability in Intracranial Vessel Diameters and Considerations for Neurovascular Models: A Systematic Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2024Article
- Tenzing 7 Delivery Catheter Performance Across Tortuosity Indices.Stroke (Hoboken, N.J.) · 2024Article
- Arterial Tortuosity Is a Potent Determinant of Safety in Endovascular Therapy for Acute Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeVessel anatomy is assumed to influence results of endovascular mechanical thrombectomy using stent retrievers. The purpose of this study was to analyze the influence of vessel curvature on recanalization results in patients with acute ischemic stroke caused by large-vessel occlusion. MATERIALS AND
methodsIn 159 patients (70 ± 12.8 years of age; 79 women) treated for acute ischemic stroke after carotid T and/or MCA occlusion by using stent retrievers, the following angles were measured in standard anteroposterior angiograms to describe vessel anatomy: first, between the terminal ICA segment and the most downward curved M1 segment conterminous to the proximal face of the thrombus (ICA/M1 angle); second, between the most proximal M1 segment and the segment immediately conterminous to the thrombus (M1/M1 angle); and additionally, in patients with distal M1/proximal M2 occlusion, the angle of the last curvature proximal of the thrombus (M1/M2 angle). Angles of patients with-versus-without successful recanalization were compared.
resultsPatients without successful recanalization (TICI 0-2a) showed significantly larger ICA/M1 angles (mean, 110°± 23.8° versus 69°± 28.7°, P < .001) and significantly larger M1/M1 angles (56°± 29.2° versus 29°± 26.6°, P = .001) than patients with successful recanalization (TICI 2b/3). In patients without successful recanalization after a distal M1 or proximal M2 occlusion, the M1/M2 angle was significantly larger than that in patients with successful recanalization (117° ± 34.3° versus 67° ± 29.5°, P = .006).
conclusionsThis retrospective analysis showed that mechanical thrombectomy in the anterior circulation was significantly less often successful in patients with large vessel angles. Therefore, vessel curvature significantly influences the results of mechanical thrombectomy with stent retrievers for treatment of acute ischemic stroke. Further work is needed to understand the underlying causality.
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