Evidence map›Paper›PMID 25634612›Full record

ArticleBlood2015

The off-target effects of nonspecific NK cells.

Dean A Lee

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Blood, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. A Hot Topic: Cancer Immunotherapy and Natural Killer Cells.International journal of molecular sciences · 2022
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dean A LeeMD ANDERSON CANCER CENTER.ORCID http://orcid.org/0000-0001-6693-5392
Scripps MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
6 · The paper itself

Abstract

In this issue of Blood, Shah et al describe the onset of severe acute graft-versus-host disease (GVHD) in 5 of 9 patients who received infusions of ex vivo expanded donor natural killer (NK) cells after HLA-matched hematopoietic stem cell transplantation (HSCT).

Indexed as

4-1BB LigandFemaleGastrointestinal NeoplasmsGraft vs Host DiseaseHumansInterleukin-15Killer Cells, NaturalMalePeripheral Blood Stem Cell TransplantationSkin Neoplasms4-1BB LigandIL15 protein, humanInterleukin-15

Identifiers

PMID25634612
OpenAlexW2160810582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.