Evidence map›Paper›PMID 25634205›Full record

Observational studyMedicine2015

Epidemiology and diagnosis of tuberculous lymphadenitis in a tuberculosis low-burden country.

Fernando Salvador, Ibai Los-Arcos, Adrián Sánchez-Montalvá, Teresa Tórtola, Adrian Curran, Ana Villar, Nuria Saborit, Josep Castellví, Israel Molina

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. XpertThe Cochrane database of systematic reviews · 2018
    Pooled it
  5. PlasmaInfectious diseases (London, England) · 2025
    Article
  6. Review
  7. Clinical characteristics and outcome of Tuberculosis lymphadenitis in a tertiary center from Saudi Arabia.Journal of clinical tuberculosis and other mycobacterial diseases · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Fernando SalvadorFrom the Department of Infectious Diseases (FS, IL-A, AS-M, AC, NS, IM), Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, PROSICS Barcelona; Department of Microbiology (TT), Vall d'Hebron University Hospital; Department of Pneumology (AV); and Department of Pathology (JC), Vall d'Hebron University Hospital, Barcelona, Spain.
Ibai Los-Arcos
Adrián Sánchez-Montalvá
Teresa Tórtola
Adrian Curran
Ana Villar
Nuria Saborit
Josep Castellví
Israel Molina
Creative Commons · USHebron University · PSChristie's · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this article is to describe epidemiological and clinical data of patients with tuberculous lymphadenitis (TL) and evaluate the yield of the diagnostic techniques employed. Retrospective observational study was performed at the Vall d'Hebron University Hospital, Barcelona, Spain. All adult patients with confirmed TL (microbiologically) or probable TL (suspected by clinical presentation, cyto/histopathological features, and clinical improvement after specific treatment) diagnosed from January 2001 to December 2013 were included. One hundred twenty-two patients were included: 78 (63.9%) patients with confirmed diagnosis and 44 (36.1%) patients with probable TL. Seventy (57.4%) patients were nonnative residents. From 83 fine-needle aspiration (FNA) specimens, 54.8% (40/73) showed granulomatous inflammation, 62.5% (40/64) had positive mycobacterial culture, and 73.3% (11/15) tested positive with Xpert MTB/RIF (Cepheid, Sunnyvale, CA). From 62 biopsy samples, 96.8% (60/62) showed granulomatous inflammation, 64.6% (31/48) had positive mycobacterial culture, and 46.1% (6/13) tested positive with Xpert MTB/RIF. TL has increasingly been diagnosed in our setting, mostly because of cases diagnosed in nonnative residents. FNA is an easy and safe technique for the diagnosis of suspected TL, and the yield regarding mycobacterial culture seems to be similar to the obtained with biopsy. The Xpert MTB/RIF test from FNA specimens may increase the accuracy of the TL diagnosis and provides quicker results.

Indexed as

AdolescentAdultAgedAged, 80 and overBiopsy, Fine-NeedleFemaleGranulomaHIV InfectionsHumansLymph NodesMaleMiddle AgedMycobacterium tuberculosisPolymerase Chain ReactionRetrospective StudiesSensitivity and Specificity

Identifiers

PMID25634205
PMCPMC4602977
OpenAlexW2329773059

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.