Evidence map›Paper›PMID 25633989›Full record

ArticlePLoS genetics2015

Ataxin-3, DNA damage repair, and SCA3 cerebellar degeneration: on the path to parsimony?

Jacqueline M Ward, Albert R La Spada

Abstract readComment
In one paragraph

Article in PLoS genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Review
  6. From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019
    Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jacqueline M WardBiomedical Sciences Graduate Program, University of California, San Diego, La Jolla, California, United States of America; Departments of Pediatrics, Cellular & Molecular Medicine, and Neurosciences, Division of Biological Sciences, the Institute for Genomic Medicine, and the Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, United States of America.
Albert R La SpadaDepartments of Pediatrics, Cellular & Molecular Medicine, and Neurosciences, Division of Biological Sciences, the Institute for Genomic Medicine, and the Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, United States of America; Rady Children's Hospital, San Diego, California, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA DamageDNA Repair EnzymesHumansMachado-Joseph DiseaseNerve Tissue ProteinsNuclear ProteinsPhosphotransferases (Alcohol Group Acceptor)Repressor ProteinsDNA Repair EnzymesNerve Tissue ProteinsNuclear ProteinsPhosphotransferases (Alcohol Group Acceptor)Repressor Proteins

Identifiers

PMID25633989
PMCPMC4310603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.