ArticleMicrobial cell factories2015
Saccharomyces cerevisiae transcriptional reprograming due to bacterial contamination during industrial scale bioethanol production.
Article in Microbial cell factories, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 71 citations in OpenAlex.
- Biofilm extracellular polysaccharides degradation during starvation and enamel demineralization.PloS one · 2017Trial
- Comparative fermentability of a glucose/xylose enriched enzymatic slurry using different yeast strains.Bioprocess and biosystems engineering · 2026Article
- Dynamics of contaminant microbes in bioethanol production from sugarcane.Journal of industrial microbiology & biotechnology · 2026Article
- Microbial ecology applied to fuel ethanol production from sugarcane.FEMS microbiology ecology · 2025Review
- Microbial Interaction between Lactiplantibacillus plantarum and Saccharomyces cerevisiae: Transcriptome Level Mechanism of Cell-Cell Antagonism.Microbiology spectrum · 2022Article
- Improvement of cell-tethered cellulase activity in recombinant strains of Saccharomyces cerevisiae.Applied microbiology and biotechnology · 2022Article
- Article
- Exploiting the Diversity of Saccharomycotina Yeasts To Engineer Biotin-Independent Growth of Saccharomyces cerevisiae.Applied and environmental microbiology · 2020Article
- Anti-Contamination Strategies for Yeast Fermentations.Microorganisms · 2020Review
- Characterization of microbial communities in ethanol biorefineries.Journal of industrial microbiology & biotechnology · 2020Article
- Review
- Interaction of 4-ethylphenol, pH, sucrose and ethanol on the growth and fermentation capacity of the industrial strain of Saccharomyces cerevisiae PE-2.World journal of microbiology & biotechnology · 2019Article
- Conventional and nonconventional strategies for controlling bacterial contamination in fuel ethanol fermentations.World journal of microbiology & biotechnology · 2018Review
- Article
- Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.Cell systems · 2017Article
- Environmental change drives accelerated adaptation through stimulated copy number variation.PLoS biology · 2017Article
- Unraveling the genetic basis of xylose consumption in engineered Saccharomyces cerevisiae strains.Scientific reports · 2016Article
- Metabolic responses to Lactobacillus plantarum contamination or bacteriophage treatment in Saccharomyces cerevisiae using a GC-MS-based metabolomics approach.World journal of microbiology & biotechnology · 2015Article
- Bioethanol strains of Saccharomyces cerevisiae characterised by microsatellite and stress resistance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe bioethanol production system used in Brazil is based on the fermentation of sucrose from sugarcane feedstock by highly adapted strains of the yeast Saccharomyces cerevisiae. Bacterial contaminants present in the distillery environment often produce yeast-bacteria cellular co-aggregation particles that resemble yeast-yeast cell adhesion (flocculation). The formation of such particles is undesirable because it slows the fermentation kinetics and reduces the overall bioethanol yield.
resultsIn this study, we investigated the molecular physiology of one of the main S. cerevisiae strains used in Brazilian bioethanol production, PE-2, under two contrasting conditions: typical fermentation, when most yeast cells are in suspension, and co-aggregated fermentation. The transcriptional profile of PE-2 was assessed by RNA-seq during industrial scale fed-batch fermentation. Comparative analysis between the two conditions revealed transcriptional profiles that were differentiated primarily by a deep gene repression in the co-aggregated samples. The data also indicated that Lactobacillus fermentum was likely the main bacterial species responsible for cellular co-aggregation and for the high levels of organic acids detected in the samples.
conclusionsHere, we report the high-resolution gene expression profiling of strain PE-2 during industrial-scale fermentations and the transcriptional reprograming observed under co-aggregation conditions. This dataset constitutes an important resource that can provide support for further development of this key yeast biocatalyst.
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