Evidence map›Paper›PMID 25633584›Full record

Trial reportTrials2015

Use of moxibustion to treat primary dysmenorrhea at two interventional times: study protocol for a randomized controlled trial.

Jie Yang, Siyi Yu, Lixing Lao, Mingxiao Yang, JianPing Chen, Xiao Luo, Yongxia Wang, Xiangzhu Chen, Juan Li, Lihua Zhu and 4 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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  3. Transcriptome Analysis of Rat Lungs Exposed to Moxa Smoke after Acute Toxicity Testing.Evidence-based complementary and alternative medicine : eCAM · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Jie YangChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. jenny_yang_jie@126.com.
Siyi YuChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. 380895114@qq.com.
Lixing LaoSchool of Chinese Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, China. lxlao1@hku.hk.
Mingxiao YangChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. mingxiaoyang@hotmail.com.
JianPing ChenChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. abchen@hku.hk.
Xiao LuoChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. 16959188@qq.com.
Yongxia WangChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. 825506684@qq.com.
Xiangzhu ChenChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. 1143026181@qq.com.
Juan LiChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. 785939016@qq.com.
Lihua ZhuChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. zlhcdzy2012@163.com.
Qianhua ZhengChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. zhengqianhua@gmail.com.
Youping HuChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. hypcdutcm@yeah.net.
Xi WuChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. wuxi403@126.com.
Fanrong LiangChengdu University of Traditional Chinese Medicine, NO.37, Shierqiao Road, Jinniu District, Chengdu, Sichuan, 610072, China. acuresearch@126.com.
Chengdu University of Traditional Chinese Medicine · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDysmenorrhea is a common menstrual complaint among adolescent girls and women of reproductive age. The treatment of dysmenorrhea is typically selected from multidisciplinary options, including complementary and alternative medicine such as acupuncture and moxibustion. However, there are few published randomized controlled trials concerning moxibustion treatment for dysmenorrhea. This trial aims to investigate the efficacy and safety of moxibustion for primary dysmenorrhea, and to identify the optimal time of moxibustion treatment for primary dysmenorrhea. METHODS/

designThis protocol is for a randomized controlled trial in which the assessor and statistician will be blinded. A total of 222 eligible patients with dysmenorrhea will be randomly assigned to three groups in a 1:1:1 ratio as treatment group A (treated before menstruation onset), treatment group B (treated at the onset of menstruation), or control group C (waiting list group). The participants assigned to the treatment groups will receive suspended moxibustion treatment at Sanyinjiao (SP6) and Guanyuan (CV4), while the waiting list group will not receive moxibustion treatment until the completion of the study. The trial period will consist of three baseline menstrual cycles, three menstrual cycles of treatment, and three menstrual cycles in the follow-up period. The primary outcome will be measured by changes in the Cox Menstrual Symptom Scale and the secondary outcomes will be measured using the Visual Analogue Scale, Cox Retrospective Symptom Scale, diary entries, the Self-rating Depression Scale, and the Self-rating Anxiety Scale. The safety of moxibustion will be assessed at every visit. DISCUSSION: This trial aims to assess the effectiveness and safety of moxibustion for primary dysmenorrhea, as well as to determine whether the optimal time of treatment for primary dysmenorrhea in clinical practice is before or after the onset of menstrual pain.

trial registrationChinese Clinical Trial Register: ChiCTR-TRC-14004627 , registered on 9 May 2014.

Indexed as

Clinical ProtocolsMoxibustionAdolescentAdultDouble-Blind MethodDysmenorrheaFemaleHumansOutcome Assessment, Health CareVisual Analog Scale

Identifiers

PMID25633584
PMCPMC4347976
OpenAlexW2163925230

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.