Evidence map›Paper›PMID 25633563›Full record

ReviewGastroenterology2015

Diagnosis, management, and investigational therapies for food allergies.

Mike Kulis, Benjamin L Wright, Stacie M Jones, A Wesley Burks

Open access · bronzeAbstract readReview
In one paragraph

Review in Gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Immunotherapy of Food Allergy: a Comprehensive Review.Clinical reviews in allergy & immunology · 2019
    Review
  6. Regional Differences in Food Allergies.Clinical reviews in allergy & immunology · 2019
    Review
  7. Analysis of Fluoride Content in Alternative Milk Beverages.The Journal of clinical pediatric dentistry · 2019
    Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mike KulisDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: mike.kulis@unc.edu.
Benjamin L WrightDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Stacie M JonesDepartment of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas.
A Wesley BurksDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
University of North Carolina at Chapel Hill · USArkansas Children's Hospital · US

Funding

RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1M
NIAID NIH HHS T32 AI007062
6 · The paper itself

Abstract

Food allergies have increased in prevalence over the past 20 years, now becoming an important public health concern. Although there are no therapies currently available for routine clinical care, recent reports have indicated that immunotherapies targeting the mucosal immune system may be effective. Oral immunotherapy is conducted by administering small, increasing amounts of food allergen; it has shown promise for desensitizing individuals with peanut, egg, or milk allergies. Sublingual immunotherapy also desensitizes allergic patients to foods-2 major studies have examined the effects of sublingual immunotherapy in subjects with peanut allergies. We review the complex nature of IgE-mediated food allergies and the therapies being evaluated in clinical trials. We focus on the diagnosis and management of food allergies and investigational therapies.

Indexed as

Sublingual ImmunotherapyTherapies, InvestigationalAllergensAnimalsBiomarkersDietFood HypersensitivityHumansImmunoglobulin EPredictive Value of TestsRisk FactorsTreatment OutcomeAllergensBiomarkersImmunoglobulin EFood AllergyOral ImmunotherapyPrevalenceSublingual Immunotherapy

Identifiers

PMID25633563
PMCPMC4793977
OpenAlexW2115244742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.