ArticleDevelopment (Cambridge, England)2015
Auxin-induced degradation dynamics set the pace for lateral root development.
Article in Development (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 82 citations in OpenAlex.
- Auxin promotes robust founder cell specification during Arabidopsis lateral root initiation.Genetics · 2026Article
- Molecular mechanisms of root expansion in medicinal plants.Frontiers in plant science · 2026Review
- Genome-Wide Identification of the ARF Gene Family in Safflower (International journal of molecular sciences · 2025Article
- Genetically Encoded, Noise-Tolerant, Auxin Biosensors in Yeast.ACS synthetic biology · 2024Article
- An atlas of Brachypodium distachyon lateral root development.Biology open · 2024Article
- Nitrate Starvation Induces Lateral Root Organogenesis inInternational journal of molecular sciences · 2024Article
- Synthetically derived BiAux modulates auxin co-receptor activity to stimulate lateral root formation.Plant physiology · 2024Article
- Genome-wide identification and expression analysis of ARF gene family in embryonic development of Korean pine (Pinus koraiensis).BMC plant biology · 2024Article
- Genome-Wide Identification and Analysis of the Aux/IAA Gene Family inInternational journal of molecular sciences · 2024Article
- Genomic survey and expression analysis of LcARFs reveal multiple functions to somatic embryogenesis in Liriodendron.BMC plant biology · 2024Article
- A non-canonicalFrontiers in plant science · 2024Article
- Identification of potential auxin response candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.Frontiers in plant science · 2024Article
- Intrinsic disorder and conformational coexistence in auxin coreceptors.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Transcription factors KNAT3 and KNAT4 are essential for integument and ovule formation in Arabidopsis.Plant physiology · 2023Article
- Dual expression and anatomy lines allow simultaneous visualization of gene expression and anatomy.Plant physiology · 2022Article
- The Systems and Synthetic Biology of Auxin.Cold Spring Harbor perspectives in biology · 2022Review
- A single-cell view of the transcriptome during lateral root initiation in Arabidopsis thaliana.The Plant cell · 2021Article
- Morphological Analysis, Protein Profiling and Expression Analysis of Auxin Homeostasis Genes of Roots of Two Contrasting Cultivars of Rice Provide Inputs on Mechanisms Involved in Rice Adaptation towards Salinity Stress.Plants (Basel, Switzerland) · 2021Article
- Expansion and innovation in auxin signaling: where do we grow from here?Development (Cambridge, England) · 2021Review
- An auxin-regulable oscillatory circuit drives the root clock inScience advances · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Auxin elicits diverse cell behaviors through a simple nuclear signaling pathway initiated by degradation of Aux/IAA co-repressors. Our previous work revealed that members of the large Arabidopsis Aux/IAA family exhibit a range of degradation rates in synthetic contexts. However, it remained an unresolved issue whether differences in Aux/IAA turnover rates played a significant role in plant responses to auxin. Here, we use the well-established model of lateral root development to directly test the hypothesis that the rate of auxin-induced Aux/IAA turnover sets the pace for auxin-regulated developmental events. We did this by generating transgenic plants expressing degradation rate variants of IAA14, a crucial determinant of lateral root initiation. Progression through the well-established stages of lateral root development was strongly correlated with the engineered rates of IAA14 turnover, leading to the conclusion that Aux/IAAs are auxin-initiated timers that synchronize developmental transitions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.