Evidence map›Paper›PMID 25632361›Full record

ArticleCase reports in ophthalmological medicine2015

Single intravitreal aflibercept injection for unilateral acute nonarteritic ischemic optic neuropathy.

Ziya Ayhan, Gamze Kocaoğlu, Aylin Yaman, Meltem Söylev Bajin, A Osman Saatci

Open access · goldAbstract read
In one paragraph

Article in Case reports in ophthalmological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ziya AyhanDepartment of Ophthalmology, Dokuz Eylül University, 35320 İzmir, Turkey.
Gamze KocaoğluDepartment of Ophthalmology, Dokuz Eylül University, 35320 İzmir, Turkey.
Aylin YamanDepartment of Ophthalmology, Dokuz Eylül University, 35320 İzmir, Turkey.ORCID 0000-0002-0391-5420
Meltem Söylev BajinDepartment of Ophthalmology, Dokuz Eylül University, 35320 İzmir, Turkey.
A Osman SaatciDepartment of Ophthalmology, Dokuz Eylül University, 35320 İzmir, Turkey.
Dokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute nonarteritic ischemic optic neuropathy (ANAION) is the most common optic neuropathy in the elderly population without a well-established treatment. A 67-year-old man with a sudden painless visual loss in his left eye of one-day duration was diagnosed to have left ANAION. Next day, 2 mg aflibercept injection was injected intravitreally in OS. Visual acuity improved to 7/10 from 1/10 a week after the injection. Mean retinal nerve fiber layer thickness (RNFLT) was reduced to 159,7 μm from 182,4 μm at the first week. Visual fields improved dramatically during the follow-up of three months. The aim of this study is to present a case having ANAION treated with a single intravitreal aflibercept injection and discuss the place of intravitreal anti-VEGF injections in the treatment of armamentarium of ANAION.

Identifiers

PMID25632361
PMCPMC4302376
OpenAlexW2047898544

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.