Evidence map›Paper›PMID 25632320›Full record

ArticleClinical and translational medicine2014

The translational significance of epithelial-mesenchymal transition in head and neck cancer.

Christian A Graves, Fadi F Abboodi, Swati Tomar, James Wells, Lucia Pirisi

Abstract read
In one paragraph

Article in Clinical and translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. A wound-healing program is hijacked to promote cancer metastasis.The Journal of experimental medicine · 2017
    Article
  9. Article
  10. Review
  11. Article
  12. HPV-p53-miR-34a axis in HPV-associated cancers.Annals of translational medicine · 2015
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian A GravesDepartment of Pathology, Microbiology & Immunology, University of South Carolina School of Medicine, Bldg. 1 Room B43 6439 Garners Ferry Rd, Columbia, SC 29208 USA ; Department of Head and Neck Surgery, Wm. Jennings Dorn VA Medical Center, Columbia, SC 29208 USA.
Fadi F AbboodiDepartment of Pathology, Microbiology & Immunology, University of South Carolina School of Medicine, Bldg. 1 Room B43 6439 Garners Ferry Rd, Columbia, SC 29208 USA.
Swati TomarDepartment of Pathology, Microbiology & Immunology, University of South Carolina School of Medicine, Bldg. 1 Room B43 6439 Garners Ferry Rd, Columbia, SC 29208 USA.
James WellsDepartment of Head and Neck Surgery, Wm. Jennings Dorn VA Medical Center, Columbia, SC 29208 USA.
Lucia PirisiDepartment of Pathology, Microbiology & Immunology, University of South Carolina School of Medicine, Bldg. 1 Room B43 6439 Garners Ferry Rd, Columbia, SC 29208 USA.

Funding

Role of HPV in Head and Neck Cancer in African Am & European Am PatientsP20MD001770 · NIMHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI CREEK, KIM E, GLOVER, SAUNDRA H · 2005 to 2014
$15.0M
NIMHD NIH HHS P20 MD001770
6 · The paper itself

Abstract

Positive markers of epithelial-mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical agents.

Indexed as

BiomarkersClinical trials in HNSCEMT and HPVEMT head and Neck cancerSlugSnailTGF beta and Head and Neck cancer

Identifiers

PMID25632320
PMCPMC4302251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.