Evidence map›Paper›PMID 25632233›Full record

ArticleInternational journal of nanomedicine2015

Physicochemical properties, cytotoxicity, and antimicrobial activity of sulphated zirconia nanoparticles.

Ae Mftah, Fatah H Alhassan, Mothanna Sadiq Al-Qubaisi, Mohamed Ezzat El Zowalaty, Thomas J Webster, Mohammed Sh-Eldin, Abdullah Rasedee, Yun Hin Taufiq-Yap, Shah Samiur Rashid

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ae MftahDepartment of Chemistry, Faculty of Industrial Sciences and Technology, University Malaysia Pahang, Malaysia.
Fatah H AlhassanCatalysis Science and Technology Research Centre, Universiti Putra Malaysia, Selangor, Malaysia ; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia.
Mothanna Sadiq Al-QubaisiInstitute of Bioscience, University Putra Malaysia, Serdang, Selangor, Malaysia.
Mohamed Ezzat El ZowalatyInstitute of Bioscience, University Putra Malaysia, Serdang, Selangor, Malaysia.
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA ; Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed Sh-EldinSolar Energy Research Institute, University Kebangsaan Malaysia, Selangor, Malaysia.
Abdullah RasedeeFaculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia.
Yun Hin Taufiq-YapCatalysis Science and Technology Research Centre, Universiti Putra Malaysia, Selangor, Malaysia ; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia.
Shah Samiur RashidDepartment of Chemistry, Faculty of Industrial Sciences and Technology, University Malaysia Pahang, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle sulphated zirconia with Brønsted acidic sites were prepared here by an impregnation reaction followed by calcination at 600°C for 3 hours. The characterization was completed using X-ray diffraction, thermal gravimetric analysis, Fourier transform infrared spectroscopy, Brunner-Emmett-Teller surface area measurements, scanning electron microscopy with energy dispersive X-ray spectroscopy, and transmission electron microscopy. Moreover, the anticancer and antimicrobial effects were investigated for the first time. This study showed for the first time that the exposure of cancer cells to sulphated zirconia nanoparticles (3.9-1,000 μg/mL for 24 hours) resulted in a dose-dependent inhibition of cell growth, as determined by (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays. Similar promising results were observed for reducing bacteria functions. In this manner, this study demonstrated that sulphated zirconia nanoparticles with Brønsted acidic sites should be further studied for a wide range of anticancer and antibacterial applications.

Indexed as

Anti-Bacterial AgentsBacteriaCell ProliferationHumansMetal NanoparticlesMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionSpectrometry, X-Ray EmissionSpectroscopy, Fourier Transform InfraredTumor Cells, CulturedX-Ray DiffractionZirconiumAnti-Bacterial AgentsZirconiumzirconium oxideanticancerantimicrobialnanoparticlessulphated zirconia

Identifiers

PMID25632233
PMCPMC4304593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.