ArticleInternational journal of nanomedicine2015
Electrochemical sensing method for point-of-care cortisol detection in human immunodeficiency virus-infected patients.
Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 76 citations in OpenAlex.
- Flexible Electrochemical Biosensor for Non-Invasive, on-Site Cortisol Monitoring in Sweat and Saliva.ACS measurement science au · 2026Article
- On-site analysis of cortisol in saliva based on microchannel lateral flow assay (mLFA) on polymer lab-on-a-chip (LOC).Biomedical microdevices · 2025Article
- Microfluidic Systems: Recent Advances in Chronic Disease Diagnosis and Their Therapeutic Management.Indian journal of microbiology · 2025Article
- Article
- The Use of Wearable Technology in Providing Assistive Solutions for Mental Well-Being.Sensors (Basel, Switzerland) · 2023Review
- Cortisol Immunosensors: A Literature Review.Biosensors · 2023Review
- Nanomaterials for Cortisol Sensing.Nanomaterials (Basel, Switzerland) · 2022Review
- Advanced wearable biosensors for the detection of body fluids and exhaled breath by graphene.Mikrochimica acta · 2022Review
- Immunosensor for Assessing the Welfare of Trainee Guide Dogs.Biosensors · 2021Article
- The perspectives of biomarker-based electrochemical immunosensors, artificial intelligence and the Internet of Medical Things toward COVID-19 diagnosis and management.Materials today. Chemistry · 2021Review
- Single-step label-free nanowell immunoassay accurately quantifies serum stress hormones within minutes.Science advances · 2021Article
- Electrochemical diagnostics of infectious viral diseases: Trends and challenges.Biosensors & bioelectronics · 2021Review
- Extended gate field-effect-transistor for sensing cortisol stress hormone.Communications materials · 2021Article
- Nano-enabled biosensing systems for intelligent healthcare: towards COVID-19 management.Materials today. Chemistry · 2020Review
- Coordinated Dispersion and Aggregation of Gold Nanorod in Aptamer-Mediated Gestational Hypertension Analysis.Journal of analytical methods in chemistry · 2019Article
- Point of Care Sensing Devices: Better Care for Everyone.Sensors (Basel, Switzerland) · 2018Article
- A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein.Scientific reports · 2018Article
- A COTS-Based Portable System to Conduct Accurate Substance Concentration Measurements.Sensors (Basel, Switzerland) · 2018Article
- Development of a Telemetric, Miniaturized Electrochemical Amperometric Analyzer.Sensors (Basel, Switzerland) · 2017Article
- Electrochemical Biosensors for Early Stage Zika Diagnostics.Trends in biotechnology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
A novel electrochemical sensing method was devised for the first time to detect plasma cortisol, a potential psychological stress biomarker, in human immunodeficiency virus (HIV)-positive subjects. A miniaturized potentiostat (reconfigured LMP91000 chip) interfaced with a microfluidic manifold containing a cortisol immunosensor was employed to demonstrate electrochemical cortisol sensing. This fully integrated and optimized electrochemical sensing device exhibited a wide cortisol-detection range from 10 pg/mL to 500 ng/mL, a low detection limit of 10 pg/mL, and sensitivity of 5.8 μA (pg mL)(-1), with a regression coefficient of 0.995. This cortisol-selective sensing system was employed to estimate plasma cortisol in ten samples from HIV patients. The electrochemical cortisol-sensing performance was validated using an enzyme-linked immunosorbent assay technique. The results obtained using both methodologies were comparable within 2%-5% variation. The information related to psychological stress of HIV patients can be correlated with disease-progression parameters to optimize diagnosis, therapeutic, and personalized health monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.