Evidence map›Paper›PMID 25632190›Full record

ArticleWorld journal of gastroenterology2015

Improvement of diabetes and hypertension after gastrectomy: a nationwide cohort study.

Eun Kyung Lee, So Young Kim, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Young Woo Kim, Jong Yeul Lee, Chan Gyoo Kim and 6 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Type 2 diabetes in patients undergoing gastric cancer surgery: areas requiring disease-specific glycemic management.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Eun Kyung LeeEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
So Young KimEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
You Jin LeeEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Mi Hyang KwakEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Hak Jin KimEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Il Ju ChoiEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Soo-Jeong ChoEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Young Woo KimEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Jong Yeul LeeEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Chan Gyoo KimEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Hong Man YoonEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Bang Wool EomEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Sun-Young KongEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Min Kyong YooEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Jong Hyock ParkEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Keun Won RyuEun Kyung Lee, You Jin Lee, Mi Hyang Kwak, Hak Jin Kim, Il Ju Choi, Soo-Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Department of Internal Medicine, National Cancer Center, Goyang 410-769, South Korea.
Kim Chaek University of Technology · KP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the effect of gastrectomy on diabetes mellitus (DM) and hypertension (HTN) in non-obese gastric cancer patients.

methodsA total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and 351 hypertensive patients with gastric cancer who had been regularly treated without chemotherapy from January 2005 to December 2010 were selected. They were divided into three groups according to their treatment methods: total gastrectomy (TG), subtotal gastrectomy (STG) and endoscopic resection (ER).

resultsThe drug discontinuation rate of anti-diabetic and anti-hypertensive agents after gastric cancer treatment was 9.7% and 11.1% respectively. DM appeared to be improved more frequently (22.8%) and earlier (mean±SE 28.6±1.8 mo) in TG group than in the two other groups [improved in 9.5% of ER group (37.4±1.1 mo) and 6.4% of STG group (47.0±0.8 mo)]. The proportion of patients treated with multiple drugs decreased more notably in TG group compared to others (P=0.001 in DM, and P=0.035 in HTN). In TG group, adjusted hazard ratio for the improvement of DM was 2.87 (95%CI: 1.15-7.17) in a multi-variate analysis and better control of DM was observed with survival analysis (P<0.001).

conclusionTG was found to decrease the need for anti-diabetic medications which can be reflective of improved glycemic control, to a greater extent than either ER or STG in non-obese diabetic patients.

Indexed as

GastrectomyAgedAntihypertensive AgentsBiomarkersBlood GlucoseBlood PressureChi-Square DistributionDiabetes MellitusDrug Therapy, CombinationFemaleGastroscopyHumansHypertensionHypoglycemic AgentsKaplan-Meier EstimateMaleAntihypertensive AgentsBiomarkersBlood GlucoseHypoglycemic AgentsDiabetesGastrectomyGastric cancerHypertensionNational cohort

Identifiers

PMID25632190
PMCPMC4306161
OpenAlexW2110337125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.