ArticleJournal of neurophysiology2015
High-speed dynamic-clamp interface.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Non-calyceal inputs gate the timing of calyx of Held evoked MNTB output.Communications biology · 2026Article
- Synaptic input variation enhances rate coding at the expense of temporal precision in cochlear nucleus neurons.PLoS biology · 2026Article
- Glycinergic axonal inhibition subserves acute spatial sensitivity to sudden increases in sound intensity.eLife · 2021Article
- Mechanisms and Functional Consequences of Presynaptic Homeostatic Plasticity at Auditory Nerve Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Minimal Number of Required Inputs for Temporally Precise Action Potential Generation in Auditory Brainstem Nuclei.Frontiers in cellular neuroscience · 2020Article
- Low Somatic Sodium Conductance Enhances Action Potential Precision in Time-Coding Auditory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Power-Law Dynamics of Membrane Conductances Increase Spiking Diversity in a Hodgkin-Huxley Model.PLoS computational biology · 2016Article
- Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5.The Journal of physiology · 2016Article
- Trends and Challenges in Neuroengineering: Toward "Intelligent" Neuroprostheses through Brain-"Brain Inspired Systems" Communication.Frontiers in neuroscience · 2016Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dynamic-clamp technique is highly useful for mimicking synaptic or voltage-gated conductances. However, its use remains rare in part because there are few systems, and they can be expensive and difficult for less-experienced programmers to implement. Furthermore, some conductances (such as sodium channels) can be quite rapid or may have complex voltage sensitivity, so high speeds are necessary. To address these issues, we have developed a new interface that uses a common personal computer platform with National Instruments data acquisition and WaveMetrics IGOR to provide a simple user interface. This dynamic clamp implements leak and linear synaptic conductances as well as a voltage-dependent synaptic conductance and kinetic channel conductances based on Hodgkin-Huxley or Markov models. The speed of the system can be assayed using a testing mode, and currently speeds of >100 kHz (10 μs per cycle) are achievable with short latency and little jitter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.