Evidence map›Paper›PMID 25631222›Full record

ArticleJournal of human hypertension2015

Sex determines cardiovascular hemodynamics in hypertension.

P Krzesiński, A Stańczyk, G Gielerak, B Uziębło-Życzkowska, M Kurpaska, K Piotrowicz, A Skrobowski

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Hypertensive women with dyspnea exhibit an unfavorable central blood pressure response to exercise.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  3. Sex Differences in Ambulatory Central Blood Pressure and Arterial Stiffness in Hemodialysis Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Exercise impedance cardiography reveals impaired hemodynamic responses to exercise in hypertensives with dyspnea.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  9. Relationships between urinary electrolytes excretion and central hemodynamics, and arterial stiffness in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  10. Article
  11. Benefits of whole-body vibration training on arterial function and muscle strength in young overweight/obese women.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  12. Abdominal obesity and hypertension: a double burden to the heart.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

P KrzesińskiDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
A StańczykDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
G GielerakDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
B Uziębło-ŻyczkowskaDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
M KurpaskaDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
K PiotrowiczDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
A SkrobowskiDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
Wojskowy Instytut Medycyny Lotniczej · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the influence of sex on cardiovascular hemodynamics and heart remodeling in 144 patients with arterial hypertension that underwent: (1) echocardiography (that is, indices of left ventricular diastolic function: e', E/e'), (2) impedance cardiography (that is, systemic vascular resistance (SVR), total artery compliance (TAC) and Heather index (HI)) and (3) applanation tonometry (augmentation index (AI), central systolic and diastolic blood pressure (CSBP, CDBP), central pulse pressure (CPP)). Women, in comparison with men, revealed to have: (1) stiffer arteries--lower TAC (1.93±0.55 vs 2.16±0.59 ml per mm Hg; P=0.025), higher CSBP (128.7±14.9 vs 123.4±13.2 mm Hg; P=0.036), CPP (39.9±9.5 vs 33.8±9.0 mm Hg; P=0.0002), AI (31.5±8.7 vs 17.5±12.7%; P<0.00001), SVR (1257.6±305.6 vs 1091.2±240.7 dyn × s × cm(-)(5); P=0.002) and (2) higher left ventricular performance--HI (16.3±4.3 vs 11.7±3.2 Ohm  × s(2); P<0.00001). In women CSBP, CPP and AI were more clearly associated with left ventricular filling pressure (e') (r=-0.39, r=-0.45, r=-0.44, P<0.01; respectively). These relations were remarkably weaker in men. Hypertensive women characterized with lower large artery compliance, more pronounced augmentation of central blood pressure and more distinctive association of central blood pressure with left ventricular diastolic function. Sex differences in cardiovascular function can impact the individualized management of arterial hypertension.

Indexed as

AdolescentAdultAgedCardiography, ImpedanceEchocardiographyFemaleHeart VentriclesHemodynamicsHumansHypertensionMaleMiddle AgedPolandPrevalenceSex FactorsYoung Adult

Identifiers

PMID25631222
OpenAlexW1971916633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.