ReviewJournal of human hypertension2015
Hypertensive epigenetics: from DNA methylation to microRNAs.
Review in Journal of human hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Epigenetic DNA Methylation and Protein Homocysteinylation: Key Players in Hypertensive Renovascular Damage.International journal of molecular sciences · 2024Review
- Histone Modifications and Their Contributions to Hypertension.Hypertension (Dallas, Tex. : 1979) · 2024Review
- Epigenetic Signatures in Hypertension.Journal of personalized medicine · 2023Article
- Association of APP gene polymorphisms and promoter methylation with essential hypertension in Guizhou: a case-control study.Human genomics · 2023Article
- Susceptibility to hypertension based onFrontiers in cardiovascular medicine · 2023Article
- Hypertensive disorders of pregnancy share common cfDNA methylation profiles.Scientific reports · 2022Article
- Predicting High Blood Pressure Using DNA Methylome-Based Machine Learning Models.Biomedicines · 2022Article
- Novel methylation mark and essential hypertension.Journal, genetic engineering & biotechnology · 2022Review
- Association of H-Type Hypertension with miR-21, miR-29, and miR-199 in Kazahks of Xinjiang, China.International journal of hypertension · 2022Article
- Insights into the Mechanisms of Fetal Growth Restriction-Induced Programming of Hypertension.Integrated blood pressure control · 2021Review
- Leucocytic DNA Methylation of Interleukin-6 Promoter Reduction in Pre-Hypertensive Young Adults.The Malaysian journal of medical sciences : MJMS · 2019Article
- Epigenetics and vascular diseases.Journal of molecular and cellular cardiology · 2019Review
- Preliminary study of the relationship between promoter methylation of the ANGPTL2 gene and coronary heart disease.Journal of clinical laboratory analysis · 2019Article
- BKHypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Hydrogen sulfide alleviates hypertensive kidney dysfunction through an epigenetic mechanism.American journal of physiology. Heart and circulatory physiology · 2017Article
- Epigenetic Modifications in Essential Hypertension.International journal of molecular sciences · 2016Review
- Lower Methylation of the ANGPTL2 Gene in Leukocytes from Post-Acute Coronary Syndrome Patients.PloS one · 2016Article
- MicroRNA network changes in the brain stem underlie the development of hypertension.Physiological genomics · 2015Article
- Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular Disease.International journal of molecular sciences · 2015Review
- Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.Redox biology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The major epigenetic features of mammalian cells include DNA methylation, posttranslational histone modifications and RNA-based mechanisms including those controlled by small non-coding RNAs (microRNAs (miRNAs)). An important aspect of epigenetic mechanisms is that they are potentially reversible and may be influenced by nutritional-environmental factors and through gene-environment interactions. Studies on epigenetic modulations could help us understand the mechanisms involved in essential hypertension and further prevent it's progress. This review is focused on new knowledge on the role of epigenetics, from DNA methylation to miRNAs, in essential hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.