ArticleSurgical endoscopy2015
Endoluminal full-thickness suture repair of gastrotomy: a survival study.
Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- True natural orifice transluminal endoscopic surgery-transgastric cholecystectomy and beyond.Clinical endoscopy · 2025Review
- Endoscopic Treatment of Anastomotic Leakage in the Upper Gastrointestinal Tract.Visceral medicine · 2025Review
- Assessment and Techniques for Endoscopic Closure.Clinics in colon and rectal surgery · 2024Review
- Robotic Platforms for Therapeutic Flexible Endoscopy: A Literature Review.Diagnostics (Basel, Switzerland) · 2024Review
- Adequate Management of Postoperative Complications after Esophagectomy: A Cornerstone for a Positive Outcome.Cancers · 2022Review
- Percutaneous Transgastric Duodenal Stenting and Gastrostomy Repair Using a Vascular Closure Device: Proof of Concept in a Porcine Model.Surgical innovation · 2022Article
- Endoscopic Closure for Full-Thickness Gastrointestinal Defects: Available Applications and Emerging Innovations.Clinical endoscopy · 2016Review
- Endoscopic full-thickness resection of gastric gastrointestinal stromal tumor: a Japanese case series.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatment of perforations and complications related to gastrointestinal (GI) surgery and interventional flexible endoscopy is increasingly performed endoscopically. New devices enabling secure full-thickness GI tract closures through flexible endoscopic platforms have been recently developed.
aimTo assess feasibility of endoscopic closure of a large gastrotomy using a tip-mounted flexible endoscopic suturing device.
methodsSix pigs were involved in this study. Standardized 3-cm full-thickness gastrotomies were created endoscopically in various areas of the gastric wall, in all animals, using monopolar cautery. A peritoneoscopy was performed through the gastrotomy. In four pigs, gastrotomy was repaired with an endoscopic suturing device (OverStitch™, Apollo Medical). Full-thickness suturing was started at the edges of the incision, and a figure-of-eight pattern was used. A dedicated helical tissue grasper combined with endoscopic suction was used to retract incision borders and ensure full-thickness closure. Sutures were locked using a cinching device. In two pigs, the gastrotomy was closed laparoscopically and served as a control. An air leak test was performed. On postoperative day 10 (POD 10), all pigs underwent endoscopy and laparotomy and were euthanized.
resultsMean endoscopic suturing time was 57.5 ± 14.15 min, and four to six sutures were delivered per incision. Laparoscopic suturing time was 8 min. All leak tests were negative. No intraoperative or postoperative complications occurred. On POD 10, all gastrotomies were healed. In one animal, thick adhesions were found surrounding the suture site but no leak was identified.
conclusionsFull-thickness suturing of experimental gastrotomies using the OverStitch™ device is feasible and effective.
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Registered trials
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