Evidence map›Paper›PMID 25630822›Full record

ArticleJournal of abnormal child psychology2016

Trajectories of Oppositional Defiant Disorder Irritability Symptoms in Preschool Children.

Lourdes Ezpeleta, Roser Granero, Núria de la Osa, Esther Trepat, Josep M Domènech

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of abnormal child psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. The Status of Irritability in Psychiatry: A Conceptual and Quantitative Review.Journal of the American Academy of Child and Adolescent Psychiatry · 2016
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genetic and Environmental Influences on the Development of Irritability from Ages 3 to 5 Years.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025
    Article
  9. Article
  10. Irritability in Youths: A Critical Integrative Review.The American journal of psychiatry · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lourdes EzpeletaUnitat d'Epidemiologia i de Diagnòstic en Psicopatologia del Desenvolupament - Grup de Recerca 2014 SGR 312 Generalitat de Catalunya, Departament de Psicologia Clínica i de la Salut, Universitat Autònoma de Barcelona, Edifici B., Bellaterra, 08193, Barcelona, Spain. Lourdes.Ezpeleta@uab.cat.
Roser GraneroUnitat d'Epidemiologia i de Diagnòstic en Psicopatologia del Desenvolupament - Grup de Recerca 2014 SGR 312 Generalitat de Catalunya, Departament de Psicobiologia i Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona, Barcelona, Spain. Roser.Granero@uab.cat.
Núria de la OsaUnitat d'Epidemiologia i de Diagnòstic en Psicopatologia del Desenvolupament - Grup de Recerca 2014 SGR 312 Generalitat de Catalunya, Departament de Psicologia Clínica i de la Salut, Universitat Autònoma de Barcelona, Edifici B., Bellaterra, 08193, Barcelona, Spain. Nuria.delaosa@uab.cat.
Esther TrepatDepartament de Psicologia Clínica i de la Salut, Universitat Autònoma de Barcelona, Edifici B., Bellaterra, 08193, Barcelona, Spain. etrepat@ipsicologia.cat.
Josep M DomènechUnitat d'Epidemiologia i de Diagnòstic en Psicopatologia del Desenvolupament - Grup de Recerca 2014 SGR 312 Generalitat de Catalunya, Departament de Psicobiologia i Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona, Barcelona, Spain. Josepmaria.domenech@uab.cat.
Universitat Autònoma de Barcelona · ESGovernment of Catalonia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThis study traces the developmental course of irritability symptoms in oppositional defiant disorder (ODD) from ages 3-5 and examines the psychopathological outcomes of the different trajectories at age 6.

methodA sample of 622 3-year-old preschoolers (311 were boys), followed up until age 6, was assessed yearly with a semi-structured diagnostic interview with parents and at age 6 with questionnaires answered by parents, teachers and children.

resultsGrowth-Mixture-Modeling yielded five trajectories of irritability levels for the whole sample (high-persistent 3.5%, decreasing 3.8%, increasing 2.6%, low-persistent 44.1% and null 46.0%). Among the children who presented with ODD during preschool age, three trajectories of irritability symptoms resulted (high-persistent 31.9%, decreasing 34.9% and increasing 33.2%). Null, low-persistent and decreasing irritability courses in the sample as a whole gave very similar discriminative capacity for children's psychopathological state at age 6, while the increasing and high-persistent categories involved poorer clinical outcomes than the null course. For ODD children, the high-persistent and increasing trajectories of irritability predicted disruptive behavior disorders, comorbidity, high level of functional impairment, internalizing and externalizing problems and low anger control at age 6.

conclusionsIrritability identifies a subset of ODD children at high risk of poorer longitudinal psychopathological and functional outcomes. It might be clinically relevant to identify this subset of ODD children with a high number of irritability symptoms throughout development with a view to preventing comorbid and future adverse longitudinal outcomes.

Indexed as

Child DevelopmentIrritable MoodAttention Deficit and Disruptive Behavior DisordersChild, PreschoolFemaleHumansLongitudinal StudiesMalePsychiatric Status Rating ScalesRisk FactorsSurveys and QuestionnairesDevelopmental trajectoriesIrritabilityOppositional defiantPreschool

Identifiers

PMID25630822
OpenAlexW2034756171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.