ReviewNeurosciences (Riyadh, Saudi Arabia)2015
Pathophysiology of carpal tunnel syndrome.
Review in Neurosciences (Riyadh, Saudi Arabia), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 113 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Soft Tissue Massage Along With Mobilization Technique on Intensity of Symptoms and Functional Status of Carpal Tunnel Syndrome - A Randomized Controlled Trial
Evaluation of Central Sensitization Parameters Based on Extra Median Symptom Distribution in Carpal Tunnel Syndrome: A Cross-sectional Study
Investigation of the Relationship Between Ultrasonographic Parameters and Tactile Sensation in Carpal Tunnel Syndrome
Combined Manual Therapy and Percutaneous Neuromodulation Versus Postsurgical Rehabilitation for Moderate Carpal Tunnel Syndrome: Protocol for a Non-Randomized Controlled Trial
Who cites it
113 citing papers in PubMed, 5 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Injection therapy for carpal tunnel syndrome: A systematic review and network meta-analysis of randomized controlled trials.PloS one · 2024Pooled it
- Local injection therapy for carpal tunnel syndrome: a network meta-analysis of randomized controlled trial.Frontiers in pharmacology · 2023Pooled it
- Can ultrasound imaging be used for the diagnosis of carpal tunnel syndrome in diabetic patients? A systemic review and network meta-analysis.Journal of neurology · 2020Pooled it
- Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank.Communications biology · 2020Pooled it
- Pooled it
- Efficacy of platelet-rich plasma as an adjuvant to surgical carpal ligament release: a prospective, randomized controlled clinical trial.Scientific reports · 2020Trial
- Tirzepatide Use Is Associated with Reduced Risk of Carpal Tunnel Syndrome in Overweight and Obese Adults.Clinical pharmacology and therapeutics · 2026Article
- The Utility of Ulnar Nerve Cross-Sectional Area in Predicting Patient Outcomes in the Early Postoperative Period.Hand (New York, N.Y.) · 2026Article
- Secondary Carpal Tunnel Syndrome Due to Flexor Tenosynovitis in a Diabetic Patient.Annals of African medicine · 2026Article
- Performance of Handwriting and Digital Typing After Carpal Tunnel Release: The TACTUS (Typing Ability in Carpal Tunnel Syndrome) Study.Journal of functional morphology and kinesiology · 2026Article
- Review
- Review
- Divergent Roles of VEGF and TNF-α in Functional Impairment Among Patients with Carpal Tunnel Syndrome.International journal of molecular sciences · 2026Article
- Health-related factors and epigenetic alterations in metabolic comorbidities patients and smokers with carpal tunnel syndrome: a preliminary investigation of patient-derived samples.Journal of orthopaedic surgery and research · 2026Article
- Ultrasonographic parameters comparison for pre- and postoperative carpal tunnel syndrome release: A single-center prospective study.Medicine · 2026Article
- Surgical Versus Conservative Management for Carpal Tunnel Syndrome: An Updated Systematic Review of Randomised Trials.Brain sciences · 2026Review
- Gabapentinoids in carpal tunnel syndrome: between clinical practice and scientific evidence.Pain management · 2026Article
- A scoping review of the impact of transverse carpal ligament sectioning on the thumb carpometacarpal joint: Does it increase the risk of ostearthritis?JPRAS open · 2026Review
- Prevalence and Risk of Carpal Tunnel Syndrome in Parkinson's Disease: A Systematic Review and Meta-Analysis.Journal of functional morphology and kinesiology · 2026Review
- Treatment Monitoring of Carpal Tunnel Syndrome Using Shear Wave Elastography: A Pilot In Vivo Study.Cureus · 2026Article
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carpal tunnel syndrome (CTS) is the most common median nerve neuropathy, accounting for 90% of all neuropathies. Carpal tunnel syndrome presents in 3.8% of the general population, with a higher prevalence among women. There are several risk factors associated with CTS, including both medical and non medical factors. The pathophysiologic mechanisms involved in the median nerve compression and traction are thought to be complex, and as yet are not fully understood. The present review aimed to provide an overview of the pathophysiology of median nerve neuropathy in the carpal tunnel, and subsequent development of CTS.
Indexed as
Identifiers
25630774PMC4727604W2120260610What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.