Evidence map›Paper›PMID 25630252›Full record

ArticleEpilepsia2015

Increasing utilization of pediatric epilepsy surgery in the United States between 1997 and 2009.

Elia M Pestana Knight, Nicholas K Schiltz, Paul M Bakaki, Siran M Koroukian, Samden D Lhatoo, Kitti Kaiboriboon

Open access · bronzeAbstract read
In one paragraph

Article in Epilepsia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 135 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A survey of paediatric epilepsy surgery in Asia and Australasia.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  5. Observational
  6. A pediatrician's guide to epilepsy surgery.Current problems in pediatric and adolescent health care · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Disparities in pediatric drug-resistant epilepsy care.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Seizure Outcomes of Epilepsy Surgery in Children.Pediatric neurology briefs · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Elia M Pestana KnightPediatric Epilepsy Section, Epilepsy Center, Cleveland Clinic Neurological Institute, Cleveland, Ohio, U.S.A.
Nicholas K Schiltz
Paul M Bakaki
Siran M Koroukian
Samden D Lhatoo
Kitti Kaiboriboon
Case Western Reserve University · USCleveland Clinic · USRainbow Babies & Children's Hospital · USSwedish Medical Center · USUniversity Hospitals Case Medical Center · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
NCATS NIH HHS UL1 TR000439NCRR NIH HHS UL1 RR024989
6 · The paper itself

Abstract

objectiveTo examine national trends of pediatric epilepsy surgery usage in the United States between 1997 and 2009.

methodsWe performed a serial cross-sectional study of pediatric epilepsy surgery using triennial data from the Kids' Inpatient Database from 1997 to 2009. The rates of epilepsy surgery for lobectomies, partial lobectomies, and hemispherectomies in each study year were calculated based on the number of prevalent epilepsy cases in the corresponding year. The age-race-sex adjusted rates of surgeries were also estimated. Mann-Kendall trend test was used to test for changes in the rates of surgeries over time. Multivariable regression analysis was also performed to estimate the effect of time, age, race, and sex on the annual incidence of epilepsy surgery.

resultsThe rates of pediatric epilepsy surgery increased significantly from 0.85 epilepsy surgeries per 1,000 children with epilepsy in 1997 to 1.44 epilepsy surgeries per 1,000 children with epilepsy in 2009. An increment in the rates of epilepsy surgeries was noted across all age groups, in boys and girls, all races, and all payer types. The rate of increase was lowest in blacks and in children with public insurance. The overall number of surgical cases for each study year was lower than 35% of children who were expected to have surgery, based on the estimates from the Connecticut Study of Epilepsy. SIGNIFICANCE: In contrast to adults, pediatric epilepsy surgery numbers have increased significantly in the past decade. However, epilepsy surgery remains an underutilized treatment for children with epilepsy. In addition, black children and those with public insurance continue to face disparities in the receipt of epilepsy surgery.

Indexed as

Neurosurgical ProceduresAdolescentAge DistributionChildChild, PreschoolCross-Sectional StudiesDatabases, FactualEpilepsyFemaleHumansIncidenceInfantInfant, NewbornMalePrevalenceRetrospective StudiesEpilepsy surgeryPediatricsTrends

Identifiers

PMID25630252
PMCPMC4363272
OpenAlexW2040524797

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.