ArticleVector borne and zoonotic diseases (Larchmont, N.Y.)2015
How important are rats as vectors of leptospirosis in the Mekong Delta of Vietnam?
Article in Vector borne and zoonotic diseases (Larchmont, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Emerging zoonotic diseases in Southeast Asia in the period 2011-2022: a systematic literature review.The veterinary quarterly · 2024Pooled it
- Spatiotemporal dynamics of the capture rate of Rattus tanezumi and its implications for rodent-borne diseases in the Three Gorges Reservoir Area, China.Environmental monitoring and assessment · 2026Article
- Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil.The Veterinary record · 2026Article
- Molecular Detection and Genotyping of PathogenicMicroorganisms · 2026Article
- Seroprevalence and carrier status ofIranian journal of veterinary research · 2025Article
- Detection ofOpen veterinary journal · 2024Article
- Leptospirosis and the Environment: A Review and Future Directions.Pathogens (Basel, Switzerland) · 2023Review
- Global Seropositivity of Swine Leptospirosis: Systematic Review and Meta-Analysis.Tropical medicine and infectious disease · 2023Review
- PathogenicMicroorganisms · 2022Article
- Prevalence of PathogenicPathogens (Basel, Switzerland) · 2022Article
- A case-control study of agricultural and behavioral factors associated with leptospirosis in Vietnam.BMC infectious diseases · 2022Article
- Clinical characteristics and prognosis of patient with leptospirosis: A multicenter retrospective analysis in south of China.Frontiers in cellular and infection microbiology · 2022Article
- Leptospira infection in rats: A literature review of global prevalence and distribution.PLoS neglected tropical diseases · 2019Review
- Prevalence of Leptospira Infection in Rodents from Bangladesh.International journal of environmental research and public health · 2019Article
- The possible zoonotic diseases transferring from pig to human in Vietnam.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- The prevalence of Leptospira among invasive small mammals on Puerto Rican cattle farms.PLoS neglected tropical diseases · 2019Article
- Detection of serum antibodies againstVeterinary world · 2019Article
- Association of rodent-borne Leptospira spp. with urban environments in Malaysian Borneo.PLoS neglected tropical diseases · 2019Article
- Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam.PloS one · 2019Article
- Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam.Viruses · 2018Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
Abstract
Leptospirosis is a zoonosis known to be endemic in the Mekong Delta of Vietnam, even though clinical reports are uncommon. We investigated leptospira infection in rats purchased in food markets during the rainy season (October) (n=150), as well as those trapped during the dry season (February-March) (n=125) in the region using RT-PCR for the lipL32 gene, confirmed by 16S rRNA, as well as by the microscopic agglutination test (MAT). Results were compared with the serovar distribution of human cases referred from Ho Chi Minh City hospitals (2004-2012) confirmed by MAT (n=45). The MAT seroprevalence among rats was 18.3%. The highest MAT seroprevalence corresponded, in decreasing order, to: Rattus norvegicus (33.0%), Bandicota indica (26.5%), Rattus tanezumi (24.6%), Rattus exulans (14.3%), and Rattus argentiventer (7.1%). The most prevalent serovars were, in descending order: Javanica (4.6% rats), Lousiana (4.2%), Copenageni (4.2%), Cynopterie (3.7%), Pomona (2.9%), and Icterohaemorrhagiae (2.5%). A total of 16 rats (5.8%) tested positive by RT-PCR. Overall, larger rats tended to have a higher prevalence of detection. There was considerable agreement between MAT and PCR (kappa=0.28 [0.07-0.49]), although significantly more rats were positive by MAT (McNemar 29.9 (p<0.001). MAT prevalence was higher among rats during the rainy season compared with rats in the dry season. There are no current available data on leptospira serovars in humans in the Mekong Delta, although existing studies suggest limited overlapping between human and rat serovars. Further studies should take into account a wider range of potential reservoirs (i.e., dogs, pigs) as well as perform geographically linked co-sampling of humans and animals to establish the main sources of leptospirosis in the region.
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