ArticlePloS one2015
Punctuated distribution of recombination hotspots and demarcation of pericentromeric regions in Phaseolus vulgaris L.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- MAGIC populations: a next-generation framework for dissecting complex quantitative traits and accelerating molecular breeding in crops.Frontiers in plant science · 2026Review
- Genome-wide association mapping dissects the selective breeding of determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.).G3 (Bethesda, Md.) · 2025Article
- Cell size differences affect photosynthetic capacity in a Mesoamerican and an Andean genotype ofFrontiers in plant science · 2024Article
- The role of recombination landscape in species hybridisation and speciation.Frontiers in plant science · 2023Review
- Dynamic QTL-based ecophysiological models to predict phenotype from genotype and environment data.BMC plant biology · 2022Article
- Novel candidate loci for morpho-agronomic and seed quality traits detected by targeted genotyping-by-sequencing in common bean.Frontiers in plant science · 2022Article
- Developmental Pleiotropy Shaped the Roots of the Domesticated Common Bean (Plant physiology · 2019Article
- Assessment of Genetic Differentiation and Linkage Disequilibrium inG3 (Bethesda, Md.) · 2019Article
- High Resolution Mapping ofFrontiers in plant science · 2019Article
- Evidence for Strong Kinship Influence on the Extent of Linkage Disequilibrium in Cultivated Common Beans.Genes · 2018Article
- High-resolution mapping of the recombination landscape of the phytopathogen Fusarium graminearum suggests two-speed genome evolution.Molecular plant pathology · 2018Article
- Does the Genomic Landscape of Species Divergence inFrontiers in plant science · 2018Article
- Genotyping by Sequencing and Genome-Environment Associations in Wild Common Bean Predict Widespread Divergent Adaptation to Drought.Frontiers in plant science · 2018Article
- Uneven recombination rate and linkage disequilibrium across a reference SNP map for common bean (Phaseolus vulgaris L.).PloS one · 2018Article
- A Predictive Model for Time-to-Flowering in the Common Bean Based on QTL and Environmental Variables.G3 (Bethesda, Md.) · 2017Article
- High-resolution mapping reveals linkage between genes in common bean cultivar Ouro Negro conferring resistance to the rust, anthracnose, and angular leaf spot diseases.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Next generation crop models: A modular approach to model early vegetative and reproductive development of the common bean (Agricultural systems · 2017Article
- Development of a QTL-environment-based predictive model for node addition rate in common bean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Fluorescence In Situ Hybridization (FISH)-Based Karyotyping Reveals Rapid Evolution of Centromeric and Subtelomeric Repeats in Common Bean (Phaseolus vulgaris) and Relatives.G3 (Bethesda, Md.) · 2016Article
- Gene-based SNP discovery in tepary bean (Phaseolus acutifolius) and common bean (P. vulgaris) for diversity analysis and comparative mapping.BMC genomics · 2016Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
High density genetic maps are a reliable tool for genetic dissection of complex plant traits. Mapping resolution is often hampered by the variable crossover and non-crossover events occurring across the genome, with pericentromeric regions (pCENR) showing highly suppressed recombination rates. The efficiency of linkage mapping can further be improved by characterizing and understanding the distribution of recombinational activity along individual chromosomes. In order to evaluate the genome wide recombination rate in common beans (Phaseolus vulgaris L.) we developed a SNP-based linkage map using the genotype-by-sequencing approach with a 188 recombinant inbred line family generated from an inter gene pool cross (Andean x Mesoamerican). We identified 1,112 SNPs that were subsequently used to construct a robust linkage map with 11 groups, comprising 513 recombinationally unique marker loci spanning 943 cM (LOD 3.0). Comparative analysis showed that the linkage map spanned >95% of the physical map, indicating that the map is almost saturated. Evaluation of genome-wide recombination rate indicated that at least 45% of the genome is highly recombinationally suppressed, and allowed us to estimate locations of pCENRs. We observed an average recombination rate of 0.25 cM/Mb in pCENRs as compared to the rest of genome that showed 3.72 cM/Mb. However, several hot spots of recombination were also detected with recombination rates reaching as high as 34 cM/Mb. Hotspots were mostly found towards the end of chromosomes, which also happened to be gene-rich regions. Analyzing relationships between linkage and physical map indicated a punctuated distribution of recombinational hot spots across the genome.
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