Evidence map›Paper›PMID 25629038›Full record

ArticleBioMed research international2015

Gender differences in cerebral regional homogeneity of adult healthy volunteers: a resting-state FMRI study.

Chunsheng Xu, Chuanfu Li, Hongli Wu, Yuanyuan Wu, Sheng Hu, Yifang Zhu, Wei Zhang, Linying Wang, Senhua Zhu, Junping Liu and 3 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
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  7. Hodge Laplacian of Brain Networks.IEEE transactions on medical imaging · 2023
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  11. Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Chunsheng XuMedical Imaging Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Institute of Computer Application of Chinese Medicine, Anhui Academy of Chinese Medicine, Anhui 230038, China.
Chuanfu LiMedical Imaging Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Institute of Computer Application of Chinese Medicine, Anhui Academy of Chinese Medicine, Anhui 230038, China.
Hongli WuLaboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Institute of Computer Application of Chinese Medicine, Anhui Academy of Chinese Medicine, Anhui 230038, China.
Yuanyuan WuGraduate School, Anhui University of Chinese Medicine, Anhui 230038, China.
Sheng HuDepartment of Electronic Science and Technology, University of Science & Technology of China, Anhui 230027, China.
Yifang ZhuMedical Imaging Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China.ORCID 0000-0002-3484-2631
Wei ZhangMedical Imaging Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China.ORCID 0000-0002-8422-4014
Linying WangGraduate School, Anhui University of Chinese Medicine, Anhui 230038, China.ORCID 0000-0001-8023-0823
Senhua ZhuInstitute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Junping LiuMedical Imaging Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China.
Qingping ZhangSchool of Acupuncture & Osteology, Anhui University of Chinese Medicine, Anhui 230038, China.
Jun YangDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 230031, China.ORCID 0000-0002-4849-7402
Xiaochu ZhangCAS Key Laboratory of Brain Function & Disease and School of Life Sciences, University of Science & Technology of China, Anhui 230027, China ; Center of Medical Physics and Technology, Hefei Institutes of Physical Science, CAS, Anhui 230031, China.ORCID 0000-0002-7541-0130
Anhui University · CNAnhui University of Traditional Chinese Medicine · CNUniversity of Science and Technology of China · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe sought to use the regional homogeneity (ReHo) approach as an index in the resting-state functional MRI to investigate the gender differences of spontaneous brain activity within cerebral cortex and resting-state networks (RSNs) in young adult healthy volunteers.

methodsOne hundred and twelve healthy volunteers (56 males, 56 females) participated in the resting-state fMRI scan. The ReHo mappings in the cerebral cortex and twelve RSNs of the male and female groups were compared.

resultsWe found statistically significant gender differences in the primary visual network (PVN) (P < 0.004, with Bonferroni correction) and left attention network (LAtN), default mode network (DMN), sensorimotor network (SMN), executive network (EN), and dorsal medial prefrontal network (DMPFC) as well (P < 0.05, uncorrected). The male group showed higher ReHo in the left precuneus, while the female group showed higher ReHo in the right middle cingulate gyrus, fusiform gyrus, left inferior parietal lobule, precentral gyrus, supramarginal gyrus, and postcentral gyrus.

conclusionsOur results suggested that men and women had regional specific differences during the resting-state. The findings may improve our understanding of the gender differences in behavior and cognition from the perspective of resting-state brain function.

Indexed as

Healthy VolunteersMagnetic Resonance ImagingSex CharacteristicsAdultBrainFemaleHumansMaleMonte Carlo MethodNerve NetRestYoung Adult

Identifiers

PMID25629038
PMCPMC4299532
OpenAlexW1993491117

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.