ReviewAmerican journal of translational research2014
Neural mechanisms and potential treatment of epilepsy and its complications.
Review in American journal of translational research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Pharmacogenetics of Carbamazepine: A Systematic Review on CYP3A4 and CYP3A5 Polymorphisms.CNS & neurological disorders drug targets · 2024Pooled it
- Machine-learning methods for epilepsy diagnosis and therapeutic prevention: advances, setbacks, and opportunities.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Prevalence and associated factors of psychiatric comorbidities in epilepsy in the Casablanca-Settat region of Morocco: A cross-sectional study.Epilepsia open · 2024Article
- Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice.Scientific reports · 2020Article
- Melanocortin-4 receptor in subthalamic nucleus is involved in the modulation of nociception.American journal of clinical and experimental immunology · 2018Article
- Pressure pain assessment may predict the outcome of spinal cord stimulation for refractory epilepsy.American journal of clinical and experimental immunology · 2018Review
- Alteration of circadian rhythm during epileptogenesis: implications for the suprachiasmatic nucleus circuits.International journal of physiology, pathophysiology and pharmacology · 2017Review
- Consciousness loss during epileptogenesis: implication for VLPO-PnO circuits.International journal of physiology, pathophysiology and pharmacology · 2017Review
- Integrated network analysis reveals potentially novel molecular mechanisms and therapeutic targets of refractory epilepsies.PloS one · 2017Article
- Role of conventional magnetic resonance imaging in the screening of epilepsy with structural abnormalities: a pictorial essay.American journal of nuclear medicine and molecular imaging · 2017Review
- Delineation of the central melanocortin circuitry controlling the kidneys by a virally mediated transsynaptic tracing study in transgenic mouse model.Oncotarget · 2016Article
- Melanocortin-4 receptor expression in the cuneiform nucleus is involved in modulation of opioidergic signaling.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Neuroanatomical evidence of the melanocortin-4 receptor expression in the mesencephalic periaqueductal gray innervating renal tissues.International journal of clinical and experimental medicine · 2015Article
- The change in cerebral glucose metabolism after electroacupuncture: a possible marker to predict the therapeutic effect of deep brain stimulation for refractory anorexia nervosa.International journal of clinical and experimental medicine · 2015Article
- Recurrent cervicodorsal spinal intradural enterogenous cyst: case report and literature review.International journal of clinical and experimental medicine · 2015Article
- Anesthetic management for craniotomy in a patient with massive cerebellar infarction and severe aortic stenosis: a case report.International journal of clinical and experimental medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The factors underlying epilepsy are multifaceted, but recent research suggests that the brain's neural circuits, which play a key role in controlling the balance between epileptic and antiepileptic factors, may lie at the heart of epilepsy. This article provides a comprehensive review of the neural mechanisms and potential treatment of intractable epilepsy from neural inflammatory responses, melanocortin circuits in brain and pedunculopontine tegmental nucleus. Further studies should be undertaken to elucidate the nature of neural circuits so that we may more effectively apply these new preventive and symptomatic therapies to the patient suffering from medically refractory seizures and its complications.
Indexed as
Identifiers
25628775PMC4297332W2346508484What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.