ReviewFrontiers in cellular neuroscience2014
Specification of excitatory neurons in the developing cerebral cortex: progenitor diversity and environmental influences.
Review in Frontiers in cellular neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Direct and indirect neurogenesis from radial glial progenitor cell clones in the mouse neocortex.The EMBO journal · 2026Article
- Molecularly defined cellular atlas of the entire mouse brain with isotropic single-cell resolution.Nature communications · 2025Article
- Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- DifferentialRegulation: a Bayesian hierarchical approach to identify differentially regulated genes.Biostatistics (Oxford, England) · 2024Article
- DifferentialRegulation: a Bayesian hierarchical approach to identify differentially regulated genes.bioRxiv : the preprint server for biology · 2024Article
- The characteristics of excitatory lineage differentiation and the developmental conservation in Reeler neocortex.Cell proliferation · 2024Article
- Mapping human tissues with highly multiplexed RNA in situ hybridization.Nature communications · 2024Article
- Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization.bioRxiv : the preprint server for biology · 2023Article
- Gene therapy ameliorates spontaneous seizures associated with cortical neuron loss in a Cln2R207X mouse model.The Journal of clinical investigation · 2023Article
- Heterogeneous fates of simultaneously-born neurons in the cortical ventricular zone.Scientific reports · 2022Article
- Role of DNMTs in the Brain.Advances in experimental medicine and biology · 2022Review
- IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype.Science advances · 2021Article
- Atypical Neurogenesis in Induced Pluripotent Stem Cells From Autistic Individuals.Biological psychiatry · 2021Article
- The Epigenome in Neurodevelopmental Disorders.Frontiers in neuroscience · 2021Review
- Autosomal Recessive Primary Microcephaly: Not Just a Small Brain.Frontiers in cell and developmental biology · 2021Review
- Transcriptomic and epigenomic dynamics associated with development of human iPSC-derived GABAergic interneurons.Human molecular genetics · 2020Article
- Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis.Cell research · 2018Article
- Specialized Subpopulations of Deep-Layer Pyramidal Neurons in the Neocortex: Bridging Cellular Properties to Functional Consequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System.Journal of visualized experiments : JoVE · 2017Article
- Article
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2 authors.
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Abstract
The mature cerebral cortex harbors a heterogeneous population of glutamatergic neurons, organized into a highly intricate histological architecture. Classically, this mixed population of neurons was thought to be generated sequentially from a seemingly homogenous group of progenitors under the influence of external cues. This view, however, has been challenged in the last decade by evidences pointing to the existence of fate-restricted neuronal progenitors in the developing neocortex. Here, we review classical studies using cell transplantation, retroviral labeling and cell culture, as well as new data from genetic fate-mapping analysis, to discuss the lineage relationships between neocortical progenitors and subclasses of excitatory neurons. We also propose a temporal model to conciliate the existence of fate-restricted progenitors alongside multipotent progenitors in the neocortex. Finally, we discuss evidences for a critical period of plasticity among post mitotic excitatory cortical neurons when environmental influences could change neuronal cell fate.
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