Evidence map›Paper›PMID 25628401›Full record

ReviewToxicological sciences : an official journal of the Society of Toxicology2015

Air pollution as a risk factor for type 2 diabetes.

Xiaoquan Rao, Priti Patel, Robin Puett, Sanjay Rajagopalan

Abstract readReview
In one paragraph

Review in Toxicological sciences : an official journal of the Society of Toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Associations of PMFrontiers in public health · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Determinants of obesity in Latin America.Nature metabolism · 2024 · on this map
    Review
  11. Article
  12. Article
  13. Article
  14. PMBMJ open diabetes research & care · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoquan Rao*Division of Cardiovascular Medicine, University of Maryland, Baltimore and Maryland Institute for Applied Environmental Health, Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park.
Priti Patel*Division of Cardiovascular Medicine, University of Maryland, Baltimore and Maryland Institute for Applied Environmental Health, Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park.
Robin Puett*Division of Cardiovascular Medicine, University of Maryland, Baltimore and Maryland Institute for Applied Environmental Health, Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park.
Sanjay Rajagopalan*Division of Cardiovascular Medicine, University of Maryland, Baltimore and Maryland Institute for Applied Environmental Health, Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park srajagopalan@medicine.umaryland.edu.

Funding

MARYLAND POPULATION RESEARCH CENTERR24HD041041 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI HOFFERTH, SANDRA L · 2001 to 2016
$6.6M
Air Pollution and Hypertension: Vascular MechanismsR01ES015146 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY · 2007 to 2018
$4.5M
Environmental Triggers of Cardiometabolic DiseaseR01ES019616 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI BROOK, ROBERT DANIEL, RAJAGOPALAN, SANJAY · 2011 to 2020
$3.0M
Air Pollution, Subclinical CVD, and Inflammatory Markers in the SEARCH CohortR01ES019168 · NIEHS · UNIV OF MARYLAND, COLLEGE PARK · PI PUETT, ROBIN · 2011 to 2014
$2.3M
Diet-Environment Interactions in InflammationR01ES017290 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY · 2010 to 2014
$1.8M
NICHD NIH HHS R24 HD041041NIEHS NIH HHS R01 ES015146NIEHS NIH HHS R0-1ES015146NIEHS NIH HHS R01 ES017290NIEHS NIH HHS R0-1ES017290NIEHS NIH HHS R01ES019168NIEHS NIH HHS R01 ES019616NIEHS NIH HHS R0-1ES019616
6 · The paper itself

Abstract

Recent studies in both humans and animals suggest that air pollution is an important risk factor for type 2 diabetes mellitus (T2DM). However, the mechanism by which air pollution mediates propensity to diabetes is not fully understood. While a number of epidemiologic studies have shown a positive association between ambient air pollution exposure and risk for T2DM, some studies have not found such a relationship. Experimental studies in susceptible disease models do support this association and suggest the involvement of tissues involved in the pathogenesis of T2DM such as the immune system, adipose, liver, and central nervous system. This review summarizes the epidemiologic and experimental evidence between ambient outdoor air pollution and T2DM.

Indexed as

Air PollutantsAir PollutionAnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2HumansInsulin ResistanceParticulate MatterRisk FactorsAir PollutantsParticulate Matter

Identifiers

PMID25628401
PMCPMC4306726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.