Evidence map›Paper›PMID 25628199›Full record

ArticleEinstein (Sao Paulo, Brazil)

Serum level of vitamin D3 in cutaneous melanoma.

Renato Santos de Oliveira Filho, Daniel Arcuschin de Oliveira, Vitor Augusto Melão Martinho, Célia Beatriz Gianotti Antoneli, Ludmilla Altino de Lima Marcussi, Carlos Eduardo dos Santos Ferreira

Open access · diamondAbstract read
In one paragraph

Article in Einstein (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Vitamins and Melanoma.Cancers · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Renato Santos de Oliveira FilhoHospital Israelita Albert Einstein, Brazil.
Daniel Arcuschin de OliveiraHospital Israelita Albert Einstein, Brazil.
Vitor Augusto Melão MartinhoHospital Israelita Albert Einstein, Brazil.
Célia Beatriz Gianotti AntoneliHospital A.C. Camargo, Brazil.
Ludmilla Altino de Lima MarcussiUniversidade Cidade de São Paulo, Brazil.
Carlos Eduardo dos Santos FerreiraHospital Israelita Albert Einstein, Brazil.
Hospital Israelita Albert Einstein · BRAC Camargo Hospital · BRUniversidade Cidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital.

methodsThe serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software.

resultsA total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency.

conclusionVitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma.

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesCholecalciferolCross-Sectional StudiesFemaleHumansMaleMelanomaMiddle AgedReference ValuesSex FactorsSkin NeoplasmsYoung AdultCholecalciferol

Identifiers

PMID25628199
PMCPMC4879914
OpenAlexW2105977796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.