Evidence map›Paper›PMID 25628116›Full record

ReviewEnvironmental science and pollution research international2015

Environmental aspects of congenital scoliosis.

Zheng Li, Xin Yu, Jianxiong Shen

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04746586 (Identification and Characterization of Circulating microRNAs as Diagnostic Biomarkers in Adolescent Idiopathic Scoliosis), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04746586 completednot on this mapstarted 2020, after this paper: background citation

Identification and Characterization of Circulating microRNAs as Diagnostic Biomarkers in Adolescent Idiopathic Scoliosis

TypeobservationalSponsorIstituto Ortopedico RizzoliRan2020 to 2025Enrolled30ConditionsAdolescent Idiopathic ScoliosisArmsCirculating MiRNA indentification
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Advances in the diagnosis and treatment of congenital scoliosis.European journal of medical research · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Core planar cell polarity genesProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Review
  12. Cross-sectional analysis of associated anomalies and vertebral anomaly location in 1289 surgical congenital scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. A comprehensive review of the diagnosis and management of congenital scoliosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zheng LiDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, 100730, Beijing, China.
Xin Yu
Jianxiong Shen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence has proved that many aspects of our lifestyle and the environment contribute to the development of congenital disease. Congenital spinal deformities are due to anomalous development of the vertebrae including failure of formation and segmentation during embryogenesis. The causes of congenital scoliosis have not been fully identified. A variety of factors are implicated in the development of vertebral abnormalities. Previous studies have demonstrated that both genetics and environmental factors are implicated in the development of vertebral abnormalities. However, no specific cause for congenital scoliosis has been identified. In our review, we focus on the environmental factors for the development of congenital scoliosis. Various maternal exposures during pregnancy including hypoxia, alcohol use, vitamin deficiency, valproic acid, boric acid, and hyperthermia have been observed to be associated with the occurrence of congenital scoliosis. This review describes the major environmental contributors of congenital scoliosis with an emphasis on treatment aspects associated with environmental disposition in congenital scoliosis.

Indexed as

Alcohol DrinkingAnimalsCarbon MonoxideEnvironmental ExposureFemaleFeverHumansPregnancyScoliosisSmokingVitamin A DeficiencyCarbon Monoxide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.