ArticleScientific reports2015
Effect of menopausal status on carotid intima-media thickness and presence of carotid plaque in Chinese women generation population.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Asymptomatic Extracranial Artery Stenosis and the Risk of Cardiovascular and Cerebrovascular Diseases.Scientific reports · 2016Trial
- Development and Validation of a Predictive Model Using Logistic Regression and Machine Learning for Carotid Artery Atherosclerosis Risk in Postmenopausal Han Women from Northern China: A Retrospective Case-Control Study.International journal of women's health · 2026Article
- Association of Life's Essential 8 Scores with Carotid Artery Plaque in Chinese Adults: A Prospective Cohort Study.Journal of atherosclerosis and thrombosis · 2025Article
- Decreased Bone Mineral Density Is Associated with Subclinical Atherosclerosis in Asymptomatic Non-Diabetic Postmenopausal Women.Journal of clinical medicine · 2025Article
- Predictors of subclinical atherosclerosis in asymptomatic healthy non-diabetic postmenopausal women.Clinical physiology and functional imaging · 2025Article
- Association of baseline Life's Essential 8 score and trajectories with carotid intima-media thickness.Frontiers in endocrinology · 2023Article
- Relation of Menopause With Cardiovascular Risk Factors in South Asian American Women (from the MASALA Study).The American journal of cardiology · 2022Article
- Relationships between menstrual status and obesity phenotypes in women: a cross-sectional study in northern China.BMC endocrine disorders · 2020Article
- Classical Cardiovascular Risk Factors and HIV are Associated With Carotid Intima-Media Thickness in Adults From Sub-Saharan Africa: Findings From H3Africa AWI-Gen Study.Journal of the American Heart Association · 2019Article
- Association between high-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2 and carotid atherosclerosis: A cross-sectional study.Journal of cellular and molecular medicine · 2018Article
- Article
- Carotid intima-media thickness and cognitive function in a middle-aged and older adult community: a cross-sectional study.Journal of neurology · 2016Article
- Association of 10-Year Atherosclerotic Cardiovascular Disease Risk Score with Carotid Intima-Media Thickness and Plaque.Korean journal of family medicine · 2015Article
- Gender difference in the response to valsartan/amlodipine single-pill combination in essential hypertension (China Status II): An observational study.Journal of the renin-angiotensin-aldosterone system : JRAASObservational
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Menopause is an important physiological stage in women's life. The potential association of menopause with carotid intima-media thickness as well as with occurrence and stability of carotid plaque in Chinese female population is unclear. We conducted a population-based, cross-sectional study by recruiting 2,131 participants aged above 40 years from northeast of China. Carotid intima-media thickness (CIMT), presence of carotid plaque and its stability were evaluated by carotid duplex sonography. Among the participants, 1,133 (53.2%) were identified to be postmenopausal. After adjusting for potential confounding factors, presence of CIMT at 50(th-) 75(th) and ≥75(th) percentiles, carotid plaque and its unstable status were found to be significantly associated with the postmenopausal status (P < 0.001). When matched the participants by age, post-menopausal status was still associated with a higher risk of having unstable plaque. Moreover, our data show that postmenopausal status is a risk factor for intracranial arterial stenosis when compared with premenopausal status in the univariate analysis (OR = 1.314, P = 0.043), and such relationship is lost when the confounding factors are adjusted (OR = 0.828, P = 0.225). In conclusion, the vascular risk factors increase as the menopausal status changes. Compared with premenopausal status, postmenopausal status is associated with higher morbidity of CIMT, carotid plaque and its unstable status.
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