Evidence map›Paper›PMID 25627324›Full record

SynthesisJournal of orthopaedic surgery and research2015

Endoscopic versus open carpal tunnel release for idiopathic carpal tunnel syndrome: a meta-analysis of randomized controlled trials.

Dongqing Zuo, Zifei Zhou, Hongsheng Wang, Yuxin Liao, Longpo Zheng, Yingqi Hua, Zhengdong Cai

Registry-linked trialAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05468814 (Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome), which is not on this map. Cited by 40 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05468814 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome: A Randomized Clinical Trial

TypeinterventionalSponsorHospital Universitario Reina Sofia de CordobaRan2022 to 2023Enrolled120ConditionsCarpal Tunnel SyndromeArmsZ-plasty, Conventional
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Local corticosteroid injection versus surgery for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2024
    Pooled it
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  6. Review
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  15. Review
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  18. Carpal Tunnel Syndrome: Open or Endoscopic Release Surgery Method?The archives of bone and joint surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dongqing ZuoDepartment of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 200072, Shanghai, China. zuozuo198@163.com.
Zifei ZhouDepartment of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 200072, Shanghai, China. smx_sy@126.com.
Hongsheng WangDepartment of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 200072, Shanghai, China. wanghs1231@gmail.com.
Yuxin LiaoDepartment of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 200072, Shanghai, China. sunmengxiong@126.com.
Longpo ZhengDepartment of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 200072, Shanghai, China. Longpozheng@163.com.
Yingqi HuaDepartment of Orthopaedics, Affiliated People's First Hospital, Shanghai Jiaotong University, 200080, Shanghai, China. zuozuo204@163.com.
Zhengdong CaiDepartment of Orthopaedics, Affiliated People's First Hospital, Shanghai Jiaotong University, 200080, Shanghai, China. zhdcai@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study is to do a meta-analysis of the literature and compare the safety and efficacy of endoscopic carpal tunnel release (ECTR) and open carpal tunnel release (OCTR) for idiopathic carpal tunnel syndrome (CTS). A comprehensive literature search of the electronic databases MEDLINE, EMBASE, Google Scholar, and the Cochrane Controlled Trial Register was undertaken for randomized studies reporting carpal tunnel syndrome treated with ECTR or OCTR. The quality of randomized trials was critically assessed. Pooled relative risk (RR) and 95% confidence intervals (CIs) for safety and efficacy outcome variables were calculated by fixed-effect or random-effect methods with RevMan v.5.1 provided by the Cochrane Collaboration. A total of 13 randomized trials were included by total retrieve and riddling. The results of our meta-analysis showed no significant difference in the overall complication rate (RR = 1.34, 95% CI [0.74, 2.43], P = 0.34), subjective satisfaction (RR = 1.0, 95% CI [0.93, 1.08], P = 0.92), time to return to work (mean difference = -3.52 [-8.15, 1.10], P = 0.14), hand grip and pinch strength, and the operative time (mean difference = -1.89, 95% CI [-5.84, 2.06]) between patients in the ECTR and OCTR groups (P = 0.16, 0.70, and 0.35, respectively). The rate of hand pain (RR = 0.73, 95% CI [0.53, 0.93], P = 0.02) in the ECTR group was significantly lower than that in the OCTR group. ECTR treatment seemed to cause more reversible postoperative nerve injuries as compared with OCTR (RR = 2.38, 95% CI [0.98, 5.77], P = 0.05). Although ECTR significantly reduced postoperative hand pain, it increased the possibility of reversible postoperative nerve injury in patients with idiopathic CTS. No statistical difference in the overall complication rate, subjective satisfaction, the time to return to work, postoperative grip and pinch strength, and operative time was observed between the two groups of patients.

Indexed as

Carpal Tunnel SyndromeEndoscopyHand StrengthHumansOperative TimePatient SatisfactionPostoperative ComplicationsRandomized Controlled Trials as TopicReturn to Work

Identifiers

PMID25627324
PMCPMC4342088

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.