SynthesisJournal of orthopaedic surgery and research2015
Endoscopic versus open carpal tunnel release for idiopathic carpal tunnel syndrome: a meta-analysis of randomized controlled trials.
Synthesis in Journal of orthopaedic surgery and research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05468814 (Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome), which is not on this map. Cited by 40 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome: A Randomized Clinical Trial
Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Local corticosteroid injection versus surgery for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2024Pooled it
- Open versus Single- or Dual-Portal Endoscopic Carpal Tunnel Release: A Meta-Analysis of Randomized Controlled Trials.Hand (New York, N.Y.) · 2023Pooled it
- Quality analysis of prior systematic reviews of carpal tunnel syndrome: an overview of the literature.Sao Paulo medical journal = Revista paulista de medicina · 2022Pooled it
- Open versus endoscopic carpal tunnel release: a systematic review and meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2020Pooled it
- Intraindividual comparison between open and endoscopic release in bilateral carpal tunnel syndrome: a meta-analysis of randomized controlled trials.Brain and behavior · 2016Pooled it
- Safety and Effectiveness of Ultrasound-Guided Carpal Tunnel Release: A Systematic Review.Journal of clinical medicine · 2026Review
- Pillar pain after carpal tunnel release: an evidence-based review of pathophysiology, diagnostic strategies, and a structured clinical decision-making framework.Annals of medicine and surgery (2012) · 2026Review
- Modified mini-open carpal tunnel release: A technical note with patient-reported and clinical outcomes.Brain & spine · 2026Article
- Minimally invasive ultrasound-guided thread carpal tunnel release: a video demonstration protocol.Journal of ultrasound · 2025Review
- Comparison of two skin closure techniques in open carpal tunnel release: a randomized controlled trial on postoperative pillar pain and scar quality.Annals of medicine and surgery (2012) · 2025Article
- Endoscopic Versus Open Carpal Tunnel Release: A Systematic Review of Outcomes and Complications.Cureus · 2024Review
- Best-Evidence Systematic Review and Meta-Analysis of Mini-Open Carpal Tunnel Release.Journal of hand surgery global online · 2024Article
- Are Patient Demographics and Payor Status Associated With Practice Patterns in the Surgical Management of Carpal Tunnel Syndrome?Hand (New York, N.Y.) · 2024Article
- Best-Evidence Systematic Review and Meta-Analysis of Endoscopic Carpal Tunnel Release Outcomes.Journal of hand surgery global online · 2023Article
- Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review.Cellular and molecular neurobiology · 2023Review
- The Association of Insurance Status and Complications After Carpal Tunnel Release.Hand (New York, N.Y.) · 2023Article
- Update on surgical procedures for carpal tunnel syndrome: What is the current evidence and practice? What are the future research directions?World journal of orthopedics · 2023Review
- Carpal Tunnel Syndrome: Open or Endoscopic Release Surgery Method?The archives of bone and joint surgery · 2022Article
- Two-port Endoscopic Surgery for Carpal Tunnel Syndrome - A Prospective Cohort Study.Malaysian orthopaedic journal · 2022Article
- Ultrasound-guided percutaneous release procedures in the transverse carpal ligament by acupotomy: A cadaveric study.Frontiers in surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study is to do a meta-analysis of the literature and compare the safety and efficacy of endoscopic carpal tunnel release (ECTR) and open carpal tunnel release (OCTR) for idiopathic carpal tunnel syndrome (CTS). A comprehensive literature search of the electronic databases MEDLINE, EMBASE, Google Scholar, and the Cochrane Controlled Trial Register was undertaken for randomized studies reporting carpal tunnel syndrome treated with ECTR or OCTR. The quality of randomized trials was critically assessed. Pooled relative risk (RR) and 95% confidence intervals (CIs) for safety and efficacy outcome variables were calculated by fixed-effect or random-effect methods with RevMan v.5.1 provided by the Cochrane Collaboration. A total of 13 randomized trials were included by total retrieve and riddling. The results of our meta-analysis showed no significant difference in the overall complication rate (RR = 1.34, 95% CI [0.74, 2.43], P = 0.34), subjective satisfaction (RR = 1.0, 95% CI [0.93, 1.08], P = 0.92), time to return to work (mean difference = -3.52 [-8.15, 1.10], P = 0.14), hand grip and pinch strength, and the operative time (mean difference = -1.89, 95% CI [-5.84, 2.06]) between patients in the ECTR and OCTR groups (P = 0.16, 0.70, and 0.35, respectively). The rate of hand pain (RR = 0.73, 95% CI [0.53, 0.93], P = 0.02) in the ECTR group was significantly lower than that in the OCTR group. ECTR treatment seemed to cause more reversible postoperative nerve injuries as compared with OCTR (RR = 2.38, 95% CI [0.98, 5.77], P = 0.05). Although ECTR significantly reduced postoperative hand pain, it increased the possibility of reversible postoperative nerve injury in patients with idiopathic CTS. No statistical difference in the overall complication rate, subjective satisfaction, the time to return to work, postoperative grip and pinch strength, and operative time was observed between the two groups of patients.
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Registered trials
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