ArticleJournal of medical microbiology2015
Non-inferiority of pulsed xenon UV light versus bleach for reducing environmental Clostridium difficile contamination on high-touch surfaces in Clostridium difficile infection isolation rooms.
Article in Journal of medical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities.International journal of environmental research and public health · 2021Pooled it
- Efficacy of Enhanced Environmental Cleaning/Disinfection Using Pulsed Xenon Ultraviolet Light in Preventing Outbreaks of Methicillin-ResistantEpidemiologia (Basel, Switzerland) · 2025Article
- The in situ efficacy of whole room disinfection devices: a literature review with practical recommendations for implementation.Antimicrobial resistance and infection control · 2022Review
- Hospital surface disinfection using ultraviolet germicidal irradiation technology: A review.Healthcare technology letters · 2022Review
- COVID-19 outbreak: Should dental and medical practices consider uv-c technology to enhance disinfection on surfaces? - A systematic review.Journal of photochemistry and photobiology · 2022Article
- Emergence and Transmission of Daptomycin and Vancomycin-Resistant Enterococci Between Patients and Hospital Rooms.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Impact of a pulsed xenon disinfection system on hospital onset Clostridioides difficile infections in 48 hospitals over a 5-year period.BMC infectious diseases · 2021Article
- Spectrum of virucidal activity from ultraviolet to infrared radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2020Article
- Impact of multicenter unified enhanced environmental cleaning and disinfection measures on nosocomial infections among patients in intensive care units.The Journal of international medical research · 2020Article
- Environmental Disinfection of a Dental Clinic during the Covid-19 Pandemic: A Narrative Insight.BioMed research international · 2020Review
- Pulsed xenon ultraviolet and non-thermal atmospheric plasma treatments are effective for the disinfection of air in hospital blood sampling rooms.Photodiagnosis and photodynamic therapy · 2019Article
- Effectiveness of ultraviolet disinfection in reducing hospital-acquired Clostridium difficile and vancomycin-resistant Enterococcus on a bone marrow transplant unit.Infection control and hospital epidemiology · 2018Article
- Update on infection control practices in cancer hospitals.CA: a cancer journal for clinicians · 2018Review
- Evaluation of a pulsed xenon ultraviolet disinfection system to decrease bacterial contamination in operating rooms.BMC infectious diseases · 2017Article
- Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.American journal of infection control · 2016Review
- Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals.Antimicrobial resistance and infection control · 2016Review
- Infection Prevention in Transplantation.Current infectious disease reports · 2016Article
- Touchless Technologies for Decontamination in the Hospital: a Review of Hydrogen Peroxide and UV Devices.Current infectious disease reports · 2015Article
- Clostridium difficile Diarrhea in the Elderly: Current Issues and Management Options.Drugs & aging · 2015Review
Corrections and comments
- Erratum issuedErratum.2015
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The standard for Clostridium difficile surface decontamination is bleach solution at a concentration of 10 % of sodium hypochlorite. Pulsed xenon UV light (PX-UV) is a means of quickly producing germicidal UV that has been shown to be effective in reducing environmental contamination by C. difficile spores. The purpose of this study was to investigate whether PX-UV was equivalent to bleach for decontamination of surfaces in C. difficile infection isolation rooms. High-touch surfaces in rooms previously occupied by C. difficile infected patients were sampled after discharge but before and after cleaning using either bleach or non-bleach cleaning followed by 15 min of PX-UV treatment. A total of 298 samples were collected by using a moistened wipe specifically designed for the removal of spores. Prior to disinfection, the mean contamination level was 2.39 c.f.u. for bleach rooms and 22.97 for UV rooms. After disinfection, the mean level of contamination for bleach was 0.71 c.f.u. (P = 0.1380), and 1.19 c.f.u. (P = 0.0017) for PX-UV disinfected rooms. The difference in final contamination levels between the two cleaning protocols was not significantly different (P = 0.9838). PX-UV disinfection appears to be at least equivalent to bleach in the ability to decrease environmental contamination with C. difficile spores. Larger studies are needed to validate this conclusion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.