ArticleThe Plant cell2015
Two distinct domains of the UVR8 photoreceptor interact with COP1 to initiate UV-B signaling in Arabidopsis.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed.
- Phosphorylation of the plant photoreceptor UVR8 regulates its dimer/monomer status and enhances UV-B signaling across species.The Plant cell · 2026Article
- UVR8-mediated UV-B signaling and its regulation of horticultural traits: from Arabidopsis to application.Horticulture research · 2026Review
- Transcription factors interact with Arabidopsis UVR8 photoreceptor at distinct sites to COP1 and RUP proteins.The Plant journal : for cell and molecular biology · 2026Article
- Conservation and divergence of UVR8 photoreceptor-mediated UV-B signaling in Marchantia polymorpha.Plant physiology · 2026Article
- Genome-wide identification of RCC1 gene family in pepper (Capsicum annuum L.) and functional analysis of CaRCC1-16 under heat stress.Plant cell reports · 2026Article
- Plant tolerance mechanisms to DNA-damaging UV stress.Journal of experimental botany · 2025Review
- The PavDREB1E-PavD8-PavHY5 module integrates light and gibberellin signals to regulate sweet cherry anthocyanin biosynthesis.Plant physiology · 2025Article
- Flavonoid pathway intermediates implicate UVR8 in functions beyond canonical UV-B signaling.Nature communications · 2025Article
- Protection of Photosynthesis by UVR8 and Cryptochromes in Arabidopsis Under Blue and UV Radiation.Plant, cell & environment · 2025Article
- The UV-B photoreceptor UVR8 interacts with the LOX1 enzyme to promote stomatal closure through the LOX-derived oxylipin pathway.The Plant cell · 2025Article
- Recent advances in UV-B signalling: interaction of proteins with the UVR8 photoreceptor.Journal of experimental botany · 2025Review
- Photoreceptor-induced sinapate synthesis contributes to photoprotection in Arabidopsis.Plant physiology · 2024Article
- Nuclear accumulation of rice UV-B photoreceptors is UV-B- and OsCOP1-independent for UV-B responses.Nature communications · 2024Article
- How Histone Acetyltransferases Shape Plant Photomorphogenesis and UV Response.International journal of molecular sciences · 2024Review
- Effects of UV-B Radiation Exposure on Transgenerational Plasticity in Grain Morphology and Proanthocyanidin Content in Yuanyang Red Rice.International journal of molecular sciences · 2024Article
- Functional divergence of Arabidopsis REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1 and 2 in repression of flowering.Plant physiology · 2024Article
- Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation.Nature communications · 2024Article
- Cross-Species Metabolomic Analyses in the Brassicaceae Reveals Common Responses to Ultraviolet-B Exposure.Plant & cell physiology · 2023Article
- RUP2 facilitates UVR8 redimerization via two interfaces.Plant communications · 2023Article
- COP1 controls salt stress tolerance by modulating sucrose content.Plant signaling & behavior · 2022Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
UV-B photon reception by the Arabidopsis thaliana homodimeric UV RESISTANCE LOCUS8 (UVR8) photoreceptor leads to its monomerization and a crucial interaction with CONSTITUTIVELY PHOTOMORPHOGENIC1 (COP1). Relay of the subsequent signal regulates UV-B-induced photomorphogenesis and stress acclimation. Here, we report that two separate domains of UVR8 interact with COP1: the β-propeller domain of UVR8 mediates UV-B-dependent interaction with the WD40 repeats-based predicted β-propeller domain of COP1, whereas COP1 activity is regulated by interaction through the UVR8 C-terminal C27 domain. We show not only that the C27 domain is required for UVR8 activity but also that chemically induced expression of the C27 domain is sufficient to mimic UV-B signaling. We further show, in contrast with COP1, that the WD40 repeat proteins REPRESSOR OF UV-B PHOTOMORPHOGENESIS1 (RUP1) and RUP2 interact only with the UVR8 C27 domain. This coincides with their facilitation of UVR8 reversion to the ground state by redimerization and their potential to interact with UVR8 in a UV-B-independent manner. Collectively, our results provide insight into a key mechanism of photoreceptor-mediated signaling and its negative feedback regulation.
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