Evidence map›Paper›PMID 25626970›Full record

ArticleInvestigative ophthalmology & visual science2015

Accommodative performance of children with unilateral amblyopia.

Vivian Manh, Angela M Chen, Kristina Tarczy-Hornoch, Susan A Cotter, T Rowan Candy

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Randomised trial of three treatments for amblyopia: Vision therapy and patching, perceptual learning and patching alone.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Trial
  2. Trial
  3. Article
  4. Longitudinal development of ocular biometric components and refractive error in children with hyperopic anisometropia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  5. The repeatability of accommodative accuracy in childhood unilateral amblyopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  6. Article
  7. Retinoscopes: Past and present.World journal of methodology · 2024
    Article
  8. Rehabilitation of amblyopia using a digital platform for visual training combined with patching in children: a prospective study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  9. Amblyopia and the whole child.Progress in retinal and eye research · 2023
    Review
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  11. Article
  12. Article
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  14. Article
  15. Article
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  18. Active efficient coding explains the development of binocular vision and its failure in amblyopia.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vivian ManhSeattle Children's Hospital, Division of Ophthalmology, Seattle, Washington, United States.
Angela M ChenSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, United States.
Kristina Tarczy-HornochSeattle Children's Hospital, Division of Ophthalmology, Seattle, Washington, United States.
Susan A CotterSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, United States.
T Rowan CandyIndiana University School of Optometry, Bloomington, Indiana, United States.

Funding

Accommodation and Defocus in the Infant Visual SystemR01EY014460 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI CANDY, T ROWAN · 2003 to 2025
$7.5M
Core Support for Vision Research at Indiana UniversityP30EY019008 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2009 to 2013
$2.1M
Early Intervention for Childhood HypermetropiaK23EY016699 · NEI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI TARCZY-HORNOCH, KRISTINA · 2005 to 2009
$854k
NEI NIH HHS K23 EY016699NEI NIH HHS P30 EY019008NEI NIH HHS R01 EY014460
6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the accommodative performance of the amblyopic eye of children with unilateral amblyopia to that of their nonamblyopic eye, and also to that of children without amblyopia, during both monocular and binocular viewing.

methodsModified Nott retinoscopy was used to measure accommodative performance of 38 subjects with unilateral amblyopia and 25 subjects with typical vision from 3 to 13 years of age during monocular and binocular viewing at target distances of 50, 33, and 25 cm. The relationship between accommodative demand and interocular difference (IOD) in accommodative error was assessed in each group.

resultsThe mean IOD in monocular accommodative error for amblyopic subjects across all three viewing distances was 0.49 diopters (D) (95% confidence interval [CI], ±1.12 D) in the 180° meridian and 0.54 D (95% CI, ±1.27 D) in the 90° meridian, with the amblyopic eye exhibiting greater accommodative errors on average. Interocular difference in monocular accommodative error increased significantly with increasing accommodative demand; 5%, 47%, and 58% of amblyopic subjects had monocular errors in the amblyopic eye that fell outside the upper 95% confidence limit for the better eye of control subjects at viewing distances of 50, 33, and 25 cm, respectively.

conclusionsWhen viewing monocularly, children with unilateral amblyopia had greater mean accommodative errors in their amblyopic eyes than in their nonamblyopic eyes, and when compared with control subjects. This could lead to unintended retinal image defocus during patching therapy for amblyopia.

Indexed as

Accommodation, OcularAdolescentAmblyopiaChildChild, PreschoolFemaleHumansMaleRetinaSeverity of Illness IndexVision, MonocularVisual Acuityaccommodationamblyopiachildren's vision

Identifiers

PMID25626970
PMCPMC4334148

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.