ArticleJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2015
How much does it cost to identify a critically ill child experiencing electrographic seizures?
Article in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 61 citations in OpenAlex.
- Implementation of 2HELPS2B Seizure Risk Score: A Cost-Effective Approach to Seizure Detection in the Intensive Care Units.Neurology. Clinical practice · 2025Article
- Article
- Point-of-Care Electroencephalography in Acute Neurological Care: A Narrative Review.Neurology international · 2025Review
- Evaluating the Impact of Point-of-Care Electroencephalography on Length of Stay in the Intensive Care Unit: Subanalysis of the SAFER-EEG Trial.Neurocritical care · 2025Article
- Observational
- Late-Onset Findings During Extended EEG Monitoring Are Rare in Critically Ill Children.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2025Article
- Optimization of continuous EEG monitoring in the inpatient setting- a quality improvement study.Frontiers in neurology · 2025Article
- Detection of neurologic changes in critically ill infants using deep learning on video data: a retrospective single center cohort study.EClinicalMedicine · 2024Article
- Accurate prediction of neurologic changes in critically ill infants using pose AI.medRxiv : the preprint server for health sciences · 2024Article
- The Cost of After-Hour Electroencephalography.Neurology. Clinical practice · 2024Article
- Neonatal Seizures in Low- and Middle-Income Countries: A Review of the Literature and Recommendations for the Management.Turkish archives of pediatrics · 2024Article
- Review of Noninvasive Neuromonitoring Modalities in Children II: EEG, qEEG.Neurocritical care · 2023Review
- Leveraging electronic medical record-embedded standardised electroencephalogram reporting to develop neonatal seizure prediction models: a retrospective cohort study.The Lancet. Digital health · 2023Article
- Continuous electroencephalography in the intensive care unit: A critical review and position statement from an Australian and New Zealand perspective.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023Article
- Variation in electroencephalography and neuroimaging for children receiving extracorporeal membrane oxygenation.Critical care (London, England) · 2023Observational
- Real-time seizure detection in paediatric intensive care patients: the RESET child brain protocol.BMJ open · 2022Article
- Continuous EEG for Diagnosis of Electrographic Seizures in the Pediatric Cardiac Critical Care Unit: Using a Precious Resource Wisely.Neurocritical care · 2022Article
- Machine learning models to predict electroencephalographic seizures in critically ill children.Seizure · 2021Observational
- EEG monitoring duration to identify electroencephalographic seizures in critically ill children.Neurology · 2020Observational
- Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury.Current neurology and neuroscience reports · 2020Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesElectrographic seizures in critically ill children may be identified by continuous EEG monitoring. We evaluated the cost effectiveness of 4 electrographic seizure identification strategies (no EEG monitoring and EEG monitoring for 1 hour, 24 hours, or 48 hours).
methodsWe created a decision tree to model the relationships among variables from a societal perspective. To provide input for the model, we estimated variable costs directly related to EEG monitoring from their component parts, and we reviewed the literature to estimate the probabilities of outcomes. We calculated incremental cost-effectiveness ratios to identify the trade-off between cost and effectiveness at different willingness-to-pay values.
resultsOur analysis found that the preferred strategy was EEG monitoring for 1 hour, 24 hours, and 48 hours if the decision maker was willing to pay <$1,666, $1,666-$22,648, and >$22,648 per critically ill child identified with electrographic seizures, respectively. The 48-hour strategy only identified 4% more children with electrographic seizures at substantially higher cost. Sensitivity analyses found that all 3 strategies were acceptable at lower willingness-to-pay values when children with higher electrographic seizure risk were monitored.
conclusionsThe results of this study support monitoring of critically ill children for 24 hours because the cost to identify a critically ill child with electrographic seizures is modest. Further study is needed to predict better which children may benefit from 48 hours of EEG monitoring because the costs are much higher.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.