ArticleBJOG : an international journal of obstetrics and gynaecology2015
Previous miscarriage and the subsequent risk of preterm birth in Scotland, 1980-2008: a historical cohort study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Obstetric and perinatal outcomes of women with a history of recurrent pregnancy loss: a meta-analysis of cohort studies.Archives of gynecology and obstetrics · 2024Pooled it
- Subsequent pregnancy outcomes after second trimester miscarriage or termination for medical/fetal reason: A systematic review and meta-analysis of observational studies.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Association of Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism with Recurrent Pregnancy Loss: a Meta-Analysis of 26 Case-Control Studies.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018Pooled it
- The amniotic fluid cell-free transcriptome in spontaneous preterm labor.Scientific reports · 2021Trial
- Spontaneous miscarriage and later lifestyle in predicting hazard of premature mortality: a cohort study in UK Biobank.Archives of gynecology and obstetrics · 2026Article
- Pregnancy Outcomes After Second Trimester Pregnancy Loss and Termination for Medical Reasons Before 24 Weeks: A Historical Cohort Study [PASTeL-2].BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Associations between maternal abortion history and neonatal outcome among very preterm infants: a multicenter cohort study.BMC pregnancy and childbirth · 2025Article
- Preterm birth recurrence after spontaneous preterm birth between 16-28 weeks: A national cohort study.European journal of obstetrics & gynecology and reproductive biology: X · 2024Article
- Association of different types of abortions with neonatal outcomes in subsequent pregnancy.Journal of global health · 2024Article
- Socioeconomic and ethnic disparities in preterm births in an English maternity setting: a population-based study of 1.3 million births.BMC medicine · 2024Article
- Development and validation of a nomogram for individualized prediction of spontaneous extremely preterm birth at < 28 weeks in twin pregnancy: a retrospective cohort study.Archives of gynecology and obstetrics · 2024Article
- Development and validation of models for predicting preterm birth and gestational latency following emergency cervical cerclage: A multicenter cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Impact of spontaneous abortion history and induced abortion history on perinatal outcomes of singleton pregnancies.BMC public health · 2023Article
- Contributors to Preterm Birth: Data from a Single Polish Perinatal Center.Children (Basel, Switzerland) · 2023Article
- Iatrogenic and spontaneous preterm birth in England: A population-based cohort study.BJOG : an international journal of obstetrics and gynaecology · 2023Article
- The risk of cardiovascular diseases after miscarriage, stillbirth, and induced abortion: a systematic review and meta-analysis.European heart journal open · 2022Article
- Maternal and Neonatal Outcomes of Women Conceived Less Than 6 Months after First Trimester Dilation and Curettage.Journal of clinical medicine · 2022Article
- Parity status and the relationship between antenatal rubella serology with obstetric outcome.Scientific reports · 2022Article
- Reproductive outcomes following recurrent first-trimester miscarriage: a retrospective cohort study.Human reproduction open · 2022Article
- Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: a nested case-control study†.Biology of reproduction · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine whether the relationship between previous miscarriage and risk of preterm birth changed over the period 1980-2008, and to determine whether the pattern varied according to the cause of the preterm birth.
designLinked birth databases.
settingAll Scottish NHS hospitals. POPULATION: A total of 732 719 nulliparous women with a first live birth between 1980 and 2008.
methodsRisk was estimated using logistic regression.
main outcome measuresPreterm birth, subdivided by cause (spontaneous, induced with a diagnosis of pre-eclampsia, or induced without a diagnosis of pre-eclampsia) and severity [extreme (24-28 weeks of gestation), moderate (29-32 weeks of gestation), and mild (33-36 weeks of gestation)].
resultsConsistent with previous studies, previous miscarriage was associated with an increased risk of all-cause preterm birth (adjusted odds ratio, aOR 1.26; 95% confidence interval, 95% CI 1.22-1.29). This arose from associations with all subtypes. The strongest association was found with extreme preterm birth (aOR 1.73; 95% CI 1.57-1.90). Risk increased with the number of miscarriages. Women with three or more miscarriages had the greatest risk of all-cause preterm birth (aOR 2.14; 95% CI 1.93-2.38), and the strongest association was with extreme preterm birth (aOR 3.87; 95% CI 2.85-5.26). The strength of the association between miscarriage and preterm birth decreased from 1980 to 2008. This was because of weakening associations with spontaneous preterm birth and induced preterm birth without a diagnosis of pre-eclampsia.
conclusionsThe association between a prior history of miscarriage and the risk of preterm birth declined in Scotland over the period 1980-2008. We speculate that changes in the methods of managing incomplete termination of pregnancy might explain the trend, through reduced cervical damage.
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