Evidence map›Paper›PMID 25625826›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2015

Phase imaging in brain using SWIFT.

Lauri Juhani Lehto, Michael Garwood, Olli Gröhn, Curtis Andrew Corum

Abstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Sub-Microsecond Switch Enabling SWIFTMagnetic resonance in medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauri Juhani LehtoDepartment of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland; Center for Magnetic Resonance Research, University of Minnesota, 2021 6th Street SE, Minneapolis, MN 55455, USA. Electronic address: lauri.lehto@uef.fi.
Michael GarwoodCenter for Magnetic Resonance Research, University of Minnesota, 2021 6th Street SE, Minneapolis, MN 55455, USA. Electronic address: gar@cmrr.umn.edu.
Olli GröhnDepartment of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. Electronic address: olli.grohn@uef.fi.
Curtis Andrew CorumCenter for Magnetic Resonance Research, University of Minnesota, 2021 6th Street SE, Minneapolis, MN 55455, USA. Electronic address: corum@cmrr.umn.edu.

Funding

NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)KL2TR000113 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$5.4M
Next Generation Pediatric Neuroimaging (NGPN) DevelopmentR44MH122028 · NIMH · CHAMPAIGN IMAGING, LLC · PI Curtis Andrew Corum · 2024 to 2026
$4.3M
Improved Breast DCE MRI with SWIFTR21CA139688 · NCI · UNIVERSITY OF MINNESOTA · PI CORUM, CURTIS ANDREW · 2009 to 2010
$527k
NCATS NIH HHS KL2 TR000113NCATS NIH HHS KL2TR000113NCI NIH HHS R21 CA139688NCI NIH HHS R21CA139688NIBIB NIH HHS P41 EB015894NIBIB NIH HHS P41EB015894NIMH NIH HHS R44 MH122028
6 · The paper itself

Abstract

The majority of MRI phase imaging is based on gradient recalled echo (GRE) sequences. This work studies phase contrast behavior due to small off-resonance frequency offsets in brain using SWIFT, a FID-based sequence with nearly zero acquisition delay. 1D simulations and a phantom study were conducted to describe the behavior of phase accumulation in SWIFT. Imaging experiments of known brain phase contrast properties were conducted in a perfused rat brain comparing GRE and SWIFT. Additionally, a human brain sample was imaged. It is demonstrated how SWIFT phase is orientation dependent and correlates well with GRE, linking SWIFT phase to similar off-resonance sources as GRE. The acquisition time is shown to be analogous to TE for phase accumulation time. Using experiments with and without a magnetization transfer preparation, the likely effect of myelin water pool contribution is seen as a phase increase for all acquisition times. Due to the phase accumulation during acquisition, SWIFT phase contrast can be sensitized to small frequency differences between white and gray matter using low acquisition bandwidths.

Indexed as

AlgorithmsSignal Processing, Computer-AssistedAnimalsBrainHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingRatsReproducibility of ResultsSensitivity and SpecificityBrainFIDGray matterMagnetization transferOrientationPhaseSWIFTWhite matter

Identifiers

PMID25625826
PMCPMC4404316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.