ArticleEmerging infectious diseases2015
Evidence for Elizabethkingia anophelis transmission from mother to infant, Hong Kong.
Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- An Update on the Novel Genera and Species and Revised Taxonomic Status of Bacterial Organisms Described in 2016 and 2017.Journal of clinical microbiology · 2019Pooled it
- Elizabethkingia in Children: A Comprehensive Review of Symptomatic Cases Reported From 1944 to 2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Pooled it
- A complex case of piperacillin-tazobactam resistant Elizabethkingia anophelis neonatal meningitis: the challenge of treatment and literature review.BMC pediatrics · 2026Review
- Review
- Genomic perspectives on the global dissemination of Elizabethkingia anophelis: unveiling inherent multidrug resistance and virulence determinants.BMC microbiology · 2026Article
- Analysis of Midgut Bacterial Communities in Larvae and Adult Mosquitoes ofMicroorganisms · 2025Article
- Genomic profiling ofFrontiers in microbiology · 2025Article
- Review
- Holy water not so holy: Potential source ofIDCases · 2025Article
- Successful Treatment of Recurrent Extensively Drug-ResistantOpen forum infectious diseases · 2024Article
- Large-scale genomic analysis of Elizabethkingia anophelis.BMC genomics · 2024Article
- Central Line-Associated Bloodstream Infection Due toMicroorganisms · 2024Article
- Whole-genome sequence and resistance determinants of four Elizabethkingia anophelis clinical isolates collected in Hanoi, Vietnam.Scientific reports · 2024Article
- Severe pneumonia caused byAmerican journal of translational research · 2024Article
- Review on infection control strategies to minimize outbreaks of the emerging pathogen Elizabethkingia anophelis.Antimicrobial resistance and infection control · 2023Review
- Article
- Article
- A rare case of community-acquiredSingapore medical journal · 2023Article
- Update on Accepted Novel Bacterial Isolates Derived from Human Clinical Specimens and Taxonomic Revisions Published in 2020 and 2021.Journal of clinical microbiology · 2023Review
- Population genomics of emergingEmerging microbes & infections · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elizabethkingia anophelis, recently discovered from mosquito gut, is an emerging bacterium associated with neonatal meningitis and nosocomial outbreaks. However, its transmission route remains unknown. We use rapid genome sequencing to investigate 3 cases of E. anophelis sepsis involving 2 neonates who had meningitis and 1 neonate's mother who had chorioamnionitis. Comparative genomics revealed evidence for perinatal vertical transmission from a mother to her neonate; the 2 isolates from these patients, HKU37 and HKU38, shared essentially identical genome sequences. In contrast, the strain from another neonate (HKU36) was genetically divergent, showing only 78.6% genome sequence identity to HKU37 and HKU38, thus excluding a clonal outbreak. Comparison to genomes from mosquito strains revealed potential metabolic adaptations in E. anophelis under different environments. Maternal infection, not mosquitoes, is most likely the source of neonatal E. anophelis infections. Our findings highlight the power of genome sequencing in gaining rapid insights on transmission and pathogenesis of emerging pathogens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.