Evidence map›Paper›PMID 25625203›Full record

ArticleDevelopmental cell2015

Hypo- or hyper-hippo: a balancing act with bHLH transcription factors.

Tiffany A Cook

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Tiffany A CookDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. Electronic address: tiffany.cook.cchmc@gmail.com.
Cincinnati Children's Hospital Medical Center · US

Funding

Molecular Networks Controlling Subtype Specification of Color PhotoreceptorsR01EY022687 · NEI · WAYNE STATE UNIVERSITY · PI COOK, TIFFANY · 2014 to 2017
$1.3M
NEI NIH HHS R01 EY022687
6 · The paper itself

Abstract

Balancing cell growth with differentiation is essential for tissue integrity. In this issue of Developmental Cell, Wang and Baker (2015) demonstrate unsuspected cross-talk between bHLH transcription factors, important regulators of organogenesis, with the Hippo tumor suppressor pathway to ensure that inappropriately differentiating cells are eliminated during development.

Indexed as

Signal TransductionAnimalsCell Cycle CheckpointsCell Cycle ProteinsDrosophila melanogasterDrosophila ProteinsHippo KinasesIntracellular Signaling Peptides and ProteinsProtein KinasesProtein Serine-Threonine KinasesCell Cycle ProteinsDrosophila ProteinsHippo Kinaseshpo protein, DrosophilaIntracellular Signaling Peptides and ProteinsProtein KinasesProtein Serine-Threonine Kinasessav protein, Drosophilawts protein, Drosophila

Identifiers

PMID25625203
PMCPMC5534332
OpenAlexW1999371172

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.