Evidence map›Paper›PMID 25625190›Full record

ArticleEmerging infectious diseases2015

Lagenidium giganteum pathogenicity in mammals.

Raquel Vilela, John W Taylor, Edward D Walker, Leonel Mendoza

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Isolation of a NovelJournal of fungi (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Leptolegnia chapmanii como alternativa biológica para el control de Aedes aegyptiBiomedica : revista del Instituto Nacional de Salud · 2019
    Article
  8. An unusual case of cutaneous feline pythiosis.Medical mycology case reports · 2019
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raquel Vilela
John W Taylor
Edward D Walker
Leonel Mendoza

Funding

Larval Mosquito Feeding and Microbial InteractionsR37AI021884 · NIAID · MICHIGAN STATE UNIVERSITY · PI WALKER, EDWARD D · 2008 to 2017
$3.7M
NIAID NIH HHS R37 AI021884NIAID NIH HHS R37AI21884
6 · The paper itself

Abstract

Infections of mammals by species in the phylum Oomycota taxonomically and molecularly similar to known Lagenidium giganteum strains have increased. During 2013-2014, we conducted a phylogenetic study of 21 mammalian Lagenidium isolates; we found that 11 cannot be differentiated from L. giganteum strains that the US Environmental Protection Agency approved for biological control of mosquitoes; these strains were later unregistered and are no longer available. L. giganteum strains pathogenic to mammals formed a strongly supported clade with the biological control isolates, and both types experimentally infected mosquito larvae. However, the strains from mammals grew well at 25°C and 37°C, whereas the biological control strains developed normally at 25°C but poorly at higher temperatures. The emergence of heat-tolerant strains of L. giganteum pathogenic to lower animals and humans is of environmental and public health concern.

Indexed as

AnimalsCulicidaeDNA, IntergenicGenes, FungalHumansInfectionsLagenidiumLarvaMammalsPhylogenyDNA, Intergenic

Identifiers

PMID25625190
PMCPMC4313650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.