Evidence map›Paper›PMID 25624401›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Epidemiological study of the association between malaria and helminth infections in Nigeria.

Akinwale Michael Efunshile, Temitope Olawale, Christen Rune Stensvold, Jørgen A L Kurtzhals, Brigitte König

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  12. Epidemiological Aspects of Blastocystis Colonization in Children in Ilero, Nigeria.The American journal of tropical medicine and hygiene · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Akinwale Michael EfunshileInstitute of Medical Microbiology and Infectious Disease Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; Federal Teaching Hospital, Abakaliki, Nigeria; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Nigeria; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, Denmark; Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark drefunshile@yahoo.com.
Temitope OlawaleInstitute of Medical Microbiology and Infectious Disease Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; Federal Teaching Hospital, Abakaliki, Nigeria; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Nigeria; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, Denmark; Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Christen Rune StensvoldInstitute of Medical Microbiology and Infectious Disease Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; Federal Teaching Hospital, Abakaliki, Nigeria; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Nigeria; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, Denmark; Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Jørgen A L KurtzhalsInstitute of Medical Microbiology and Infectious Disease Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; Federal Teaching Hospital, Abakaliki, Nigeria; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Nigeria; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, Denmark; Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Brigitte KönigInstitute of Medical Microbiology and Infectious Disease Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; Federal Teaching Hospital, Abakaliki, Nigeria; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Nigeria; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark; Centre for Medical Parasitology, Department of Clinical Microbiology, Copenhagen University Hospital, Copenhagen, Denmark; Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between intestinal helminth infection and susceptibility to malaria remains unclear. We studied the relationship between these infections. Seven schools in Ilero, Nigeria referred all pupils with febrile illness to our study center for free malaria treatment during a 3-month study period. At the end, all pupils submitted a stool sample for microscopic investigation for helminth eggs. We used an unmatched case-control design to calculate the odds ratios for helminth infection in children with at least one attack of malaria (cases) and children with no malaria episodes during the study (controls). We recorded 115 malaria cases in 82 of 354 (23.2%), 16 of 736 (2.2%), and 17 of 348 (4.7%) children ages ≤ 5, 6-10, and 11-15 years old, respectively (P = 0.001). Helminth infection rate in cases was 21 of 115 (18.3%) compared with 456 of 1,327 (34.4%) in controls. Weighted odds ratio stratified by age group for helminth infection in cases versus controls was 0.50 (95% confidence interval = 0.2-0.84, P < 0.01). Ascaris and hookworm were the most common helminths detected, with prevalence rates of 14 (12.2%) and 6 (5.2%) among cases compared with 333 (25.1%) and 132 (10.0%) in controls, respectively (P = 0.001). The negative association between helminth infection and malaria may be of importance in the design of deworming programs.

Indexed as

AdolescentChildChild, PreschoolCoinfectionFemaleHelminthiasisHumansMalariaMaleNigeria

Identifiers

PMID25624401
PMCPMC4350553
OpenAlexW2318253353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.